* installing *source* package ‘nlmixr2est’ ... ** package ‘nlmixr2est’ successfully unpacked and MD5 sums checked ** using staged installation --------[begin src/Makevars]-------- # -*- mode: makefile-gmake -*- ARMA=/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include BH=/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include RCPP=/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include RXP=/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include CXX_STD = CXX17 PKG_LIBS = $(LAPACK_LIBS) $(BLAS_LIBS) $(FLIBS) $(SHLIB_OPENMP_CXXFLAGS) PKG_CXXFLAGS = -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"$(BH)" -isystem"$(RCPP)" -isystem"$(ARMA)" -isystem"$(RXP)" $(SHLIB_OPENMP_CXXFLAGS) -DARMA_64BIT_WORD=1 SHLIB_LDFLAGS = $(SHLIB_CXXLDFLAGS) SHLIB_LD = $(SHLIB_CXXLD) SOURCES_C = init.c rprintf.c merge3.c lbfgsR.c utilc.c SOURCES_CPP = uninformativeEtas.cpp nlm.cpp filterNormalLike.cpp inner.cpp shi21.cpp nearPD.cpp censEst.cpp saem.cpp expandNlme.cpp npde.cpp shrink.cpp ires.cpp res.cpp cwres.cpp censResid.cpp cholse.cpp neldermead.cpp resid.cpp slice.cpp RcppExportMod.cpp RcppExports.cpp OBJECTS = $(SOURCES_CPP:.cpp=.o) $(SOURCES_C:.c=.o) all: $(SHLIB) $(SHLIB): $(OBJECTS) --------[end src/Makevars]-------- ** libs using C compiler: ‘Apple clang version 14.0.3 (clang-1403.0.22.14.1)’ using C++ compiler: ‘Apple clang version 14.0.3 (clang-1403.0.22.14.1)’ using C++17 using SDK: ‘MacOSX11.3.sdk’ clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c uninformativeEtas.cpp -o uninformativeEtas.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c nlm.cpp -o nlm.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c filterNormalLike.cpp -o filterNormalLike.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c inner.cpp -o inner.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c shi21.cpp -o shi21.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c nearPD.cpp -o nearPD.o nlm.cpp:399:7: warning: unused variable 'cores' [-Wunused-variable] int cores = getOpCores(op); ^ nlm.cpp:525:7: warning: unused variable 'cores' [-Wunused-variable] int cores = getOpCores(op); ^ nlm.cpp:608:12: warning: unused variable 'llik' [-Wunused-variable] double llik; ^ inner.cpp:3153:26: warning: variable 'k' set but not used [-Wunused-but-set-variable] unsigned int i, j = 0, k = 0, ii=0, jj = 0, iA=0, iB=0, iH=0, iVid=0, iLO=0; ^ inner.cpp:3153:59: warning: variable 'iH' set but not used [-Wunused-but-set-variable] unsigned int i, j = 0, k = 0, ii=0, jj = 0, iA=0, iB=0, iH=0, iVid=0, iLO=0; ^ clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" 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-isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c saem.cpp -o saem.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c expandNlme.cpp -o expandNlme.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c npde.cpp -o npde.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c shrink.cpp -o shrink.o 3 warnings generated. clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c ires.cpp -o ires.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c res.cpp -o res.o npde.cpp:129:15: warning: variable 'hi' set but not used [-Wunused-but-set-variable] double low, hi, low2, hi2; ^ res.cpp:17:7: warning: unused variable 'idSize' [-Wunused-variable] int idSize = ID.size(); ^ clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c cwres.cpp -o cwres.o 1 warning generated. clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c censResid.cpp -o censResid.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c cholse.cpp -o cholse.o 1 warning generated. clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c neldermead.cpp -o neldermead.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c resid.cpp -o resid.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c slice.cpp -o slice.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c RcppExportMod.cpp -o RcppExportMod.o clang++ -arch x86_64 -std=gnu++17 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -Id -I../inst/include -DBOOST_DISABLE_ASSERTS -DBOOST_NO_CXX11_STATIC_ASSERT -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include" -isystem"/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include" -DARMA_64BIT_WORD=1 -fPIC -falign-functions=64 -Wall -g -O2 -c RcppExports.cpp -o RcppExports.o clang -arch x86_64 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -fPIC -falign-functions=64 -Wall -g -O2 -c init.c -o init.o clang -arch x86_64 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -fPIC -falign-functions=64 -Wall -g -O2 -c rprintf.c -o rprintf.o clang -arch x86_64 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -fPIC -falign-functions=64 -Wall -g -O2 -c merge3.c -o merge3.o clang -arch x86_64 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -fPIC -falign-functions=64 -Wall -g -O2 -c lbfgsR.c -o lbfgsR.o clang -arch x86_64 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/BH/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/n1qn1/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lbfgsb3c/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/lotri/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/Rcpp/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppArmadillo/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include' -I'/Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/rxode2/include' -I/opt/R/x86_64/include -fPIC -falign-functions=64 -Wall -g -O2 -c utilc.c -o utilc.o In file included from RcppExports.cpp:4: In file included from ./../inst/include/nlmixr2est.h:7: In file included from ../inst/include/nlmixr2est_RcppExports.h:8: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/RcppEigen.h:25: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/RcppEigenForward.h:29: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/Eigen/Sparse:26: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/Eigen/SparseCore:61: /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/Eigen/src/SparseCore/TriangularSolver.h:273:13: warning: variable 'count' set but not used [-Wunused-but-set-variable] Index count = 0; ^ In file included from RcppExports.cpp:4: In file included from ./../inst/include/nlmixr2est.h:7: In file included from ../inst/include/nlmixr2est_RcppExports.h:8: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/RcppEigen.h:25: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/RcppEigenForward.h:29: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/Eigen/Sparse:29: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/Eigen/SparseLU:35: /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/Eigen/src/SparseLU/SparseLU_heap_relax_snode.h:78:9: warning: variable 'nsuper_et_post' set but not used [-Wunused-but-set-variable] Index nsuper_et_post = 0; // Number of relaxed snodes in postordered etree ^ /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/Eigen/src/SparseLU/SparseLU_heap_relax_snode.h:79:9: warning: variable 'nsuper_et' set but not used [-Wunused-but-set-variable] Index nsuper_et = 0; // Number of relaxed snodes in the original etree ^ 2 warnings generated. In file included from RcppExports.cpp:4: In file included from ./../inst/include/nlmixr2est.h:7: In file included from ../inst/include/nlmixr2est_RcppExports.h:8: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/RcppEigen.h:25: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/RcppEigenForward.h:31: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/unsupported/Eigen/IterativeSolvers:46: /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/unsupported/Eigen/src/IterativeSolvers/IDRS.h:72:10: warning: variable 'replacements' set but not used [-Wunused-but-set-variable] Index replacements = 0; ^ In file included from RcppExports.cpp:4: In file included from ./../inst/include/nlmixr2est.h:7: In file included from ../inst/include/nlmixr2est_RcppExports.h:8: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/RcppEigen.h:25: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/RcppEigenForward.h:37: In file included from /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/unsupported/Eigen/SparseExtra:45: /Volumes/Builds/packages/big-sur-x86_64/Rlib/4.4/RcppEigen/include/unsupported/Eigen/src/SparseExtra/MarketIO.h:246:7: warning: variable 'count' set but not used [-Wunused-but-set-variable] int count = 0; ^ 5 warnings generated. clang++ -arch x86_64 -std=gnu++17 -dynamiclib -Wl,-headerpad_max_install_names -undefined dynamic_lookup -L/Library/Frameworks/R.framework/Resources/lib -L/opt/R/x86_64/lib -o nlmixr2est.so uninformativeEtas.o nlm.o filterNormalLike.o inner.o shi21.o nearPD.o censEst.o saem.o expandNlme.o npde.o shrink.o ires.o res.o cwres.o censResid.o cholse.o neldermead.o resid.o slice.o RcppExportMod.o RcppExports.o init.o rprintf.o merge3.o lbfgsR.o utilc.o -L/Library/Frameworks/R.framework/Resources/lib -lRlapack -L/Library/Frameworks/R.framework/Resources/lib -lRblas -L/opt/gfortran/lib/gcc/x86_64-apple-darwin20.0/12.2.0 -L/opt/gfortran/lib -lgfortran -lquadmath -F/Library/Frameworks/R.framework/.. -framework R -Wl,-framework -Wl,CoreFoundation installing to /Volumes/Builds/packages/big-sur-x86_64/results/4.4/nlmixr2est.Rcheck/00LOCK-nlmixr2est/00new/nlmixr2est/libs ** generating debug symbols (dSYM) ** R ** data *** moving datasets to lazyload DB ** inst ** byte-compile and prepare package for lazy loading ** help *** installing help indices *** copying figures ** building package indices ** testing if installed package can be loaded from temporary location ** checking absolute paths in shared objects and dynamic libraries ** testing if installed package can be loaded from final location ** testing if installed package keeps a record of temporary installation path * DONE (nlmixr2est)