Running ‘spelling.R’ [0s/1s]
  Running ‘testthat.R’ [80s/72s]
Running the tests in ‘tests/testthat.R’ failed.
Complete output:
  > # This file is part of the standard setup for testthat.
  > # It is recommended that you do not modify it.
  > #
  > # Where should you do additional test configuration?
  > # Learn more about the roles of various files in:
  > # * https://r-pkgs.org/tests.html
  > # * https://testthat.r-lib.org/reference/test_package.html#special-files
  > 
  > library(testthat)
  > library(Colossus)
  > 
  > test_check("Colossus")
  Saving 7 x 7 in image
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 2 risk groups
  Note: 2 risk groups
  Note: Starting Plot Function
  Note: Getting Plot Info
  Error: no events
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 2 risk groups
  Error: Plot type not given
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 2 risk groups
  Error: Stratification Column not in dataframe
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 2 risk groups
  Error: Stratification Column not given
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 2 risk groups
  Error: dose column not given
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 2 risk groups
  Error: dose column not given
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 2 risk groups
  Error: ID column is not in the dataframe
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 2 risk groups
  Error: ID column not given
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 3 risk groups
  Note: 3 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:00:50 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,93,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:50 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 307 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:50 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: ending guess 0
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1, 0<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  Note: starting ph_plot
  C++ Note: START_PLOT
  C++ Note: Current Time, Fri Sep 29 06:00:50 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,52,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:50 2023
  
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Grouping Start
  C++ Note: df100 2307 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:50 2023
  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  Note: writing survival data
  Note: Plotting Survival Curves
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 3 risk groups
  Note: 3 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:00:52 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,58,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:52 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 245 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:52 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: ending guess 0
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1, 0<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  Note: starting ph_plot
  C++ Note: START_PLOT
  C++ Note: Current Time, Fri Sep 29 06:00:52 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,1329,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:52 2023
  
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Grouping Start
  C++ Note: df100 2552 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:52 2023
  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  Note: writing survival data
  Note: Plotting Survival Curves
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Note: 2  strata used
  Note: 2  strata used
  Note: 3 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:00:54 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,67,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:54 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 256 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:54 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 0.606531 1.2374  
  C++ Note: riskl checked 0.606531 1.2374  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 0.606531 1.2374  
  C++ Note: riskl checked 0.606531 1.2374  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: ending guess 0
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1, 0<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 0.606531 1.2374  
  C++ Note: riskl checked 0.606531 1.2374  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 0.606531 1.2374  
  C++ Note: riskl checked 0.606531 1.2374  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  Note: Starting Stratification:  0
  C++ Note: START_PLOT
  C++ Note: Current Time, Fri Sep 29 06:00:54 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,59,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:54 2023
  
  C++ Note: values checked -0.1  
  C++ Note: sums checked 1.60467  
  C++ Note: derivs checked 9.92015  
  C++ Note: second derivs checked 63.6775  
  C++ Note: dose checked 3  
  C++ Note: non-dose checked 1.60467  
  C++ Note: LIN_non-dose checked 3  
  C++ Note: PLIN_non-dose checked 3  
  C++ Note: LOGLIN_non-dose checked 1.60467  
  C++ Note: risk checked 1.60467  
  C++ Note: risk1 checked 9.92015  
  C++ Note: risk2 checked 63.6775  
  C++ Note: Grouping Start
  C++ Note: df100 489 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:54 2023
  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 0.606531  
  C++ Note: risk1r checked 3.03265  
  C++ Note: risk2r checked 15.1633  
  C++ Note: riskl checked 0.606531  
  C++ Note: risk1l checked 3.03265  
  C++ Note: risk2l checked 15.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  Note: Starting Stratification:  1
  C++ Note: START_PLOT
  C++ Note: Current Time, Fri Sep 29 06:00:54 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,72,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:54 2023
  
  C++ Note: values checked -0.1  
  C++ Note: sums checked 2.31429  
  C++ Note: derivs checked 12.039  
  C++ Note: second derivs checked 74.6573  
  C++ Note: dose checked 4  
  C++ Note: non-dose checked 2.31429  
  C++ Note: LIN_non-dose checked 4  
  C++ Note: PLIN_non-dose checked 4  
  C++ Note: LOGLIN_non-dose checked 2.31429  
  C++ Note: risk checked 2.31429  
  C++ Note: risk1 checked 12.039  
  C++ Note: risk2 checked 74.6573  
  C++ Note: Grouping Start
  C++ Note: df100 605 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:54 2023
  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.2374  
  C++ Note: risk1r checked 5.69855  
  C++ Note: risk2r checked 31  
  C++ Note: riskl checked 1.2374  
  C++ Note: risk1l checked 5.69855  
  C++ Note: risk2l checked 31  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  Saving 7 x 7 in image
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 3 risk groups
  Note: 3 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:00:55 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,67,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:55 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 240 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:55 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: ending guess 0
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1, 0<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  C++ Note: START_PLOT
  C++ Note: Current Time, Fri Sep 29 06:00:55 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,119,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:55 2023
  
  C++ Note: values checked -0.1  
  C++ Note: sums checked 5.29005  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 5.29005  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 5.29005  
  C++ Note: risk checked 5.29005  
  Saving 7 x 7 in image
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 86 risk groups
  Note: 86 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:00:56 2023
  
  C++ Note: Term checked 0 1  
  C++ Note: df99,62,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:56 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 3449 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:56 2023
  
  C++ Note: starting subterms 2 in guess 0
  C++ Note: values checked 0.01 -15  
  C++ Note: sums checked 6437.95 3328  
  C++ Note: derivs checked 3813.95 0.000939732  
  C++ Note: second derivs checked 3813.95 0.000939732  
  C++ Note: dose checked 6400 6400  
  C++ Note: non-dose checked 6437.95 3328  
  C++ Note: LIN_non-dose checked 6400 6400  
  C++ Note: PLIN_non-dose checked 6400 6400  
  C++ Note: LOGLIN_non-dose checked 6437.95 3328  
  C++ Note: risk checked 9787.82  
  C++ Note: risk1 checked 6011.82 0.000944651  
  C++ Note: risk2 checked 6011.82 0.000944651  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 6489.99  
  C++ Note: risk1r checked 4018.99 0.000575324  
  C++ Note: risk2r checked 4018.99 0.000575324  
  C++ Note: riskl checked 119.492  
  C++ Note: risk1l checked 49.4925 1.62651e-05  
  C++ Note: risk2l checked 49.4925 1.62651e-05  
  C++ Note: df101 -329.891 -329.891  
  C++ Note: df102 -21.7852 9.27193e-06  
  C++ Note: df103 -19.521 9.27193e-06  
  C++ Note: df104 0.01 -15  
  C++ Note: df105 1.11599 1  
  C++ Note: df106 15.1429 -3.55796e+07  
  C++ Note: riskr checked 6489.99  
  C++ Note: risk1r checked 4018.99 0.000575324  
  C++ Note: risk2r checked 4018.99 0.000575324  
  C++ Note: riskl checked 119.492  
  C++ Note: risk1l checked 49.4925 1.62651e-05  
  C++ Note: risk2l checked 49.4925 1.62651e-05  
  C++ Note: df101 -329.891 -329.891  
  C++ Note: df102 -21.7852 9.27193e-06  
  C++ Note: df103 -19.521 9.27193e-06  
  C++ Note: df104 0.01 -15  
  C++ Note: df105 1.11599 1  
  C++ Note: df106 15.1429 -3.55796e+07  
  C++ Note: ending guess 0
  C++ Note: df501 -329.8914
  C++ Note: df504 0.01 -15  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.01 -15, -329.8914<-- Best Guess
  C++ Note: starting subterms 2 in best guess 0
  C++ Note: values checked 0.01 -15  
  C++ Note: sums checked 6437.95 3328  
  C++ Note: derivs checked 3813.95 0.000939732  
  C++ Note: second derivs checked 3813.95 0.000939732  
  C++ Note: dose checked 6400 6400  
  C++ Note: non-dose checked 6437.95 3328  
  C++ Note: LIN_non-dose checked 6400 6400  
  C++ Note: PLIN_non-dose checked 6400 6400  
  C++ Note: LOGLIN_non-dose checked 6437.95 3328  
  C++ Note: risk checked 9787.82  
  C++ Note: risk1 checked 6011.82 0.000944651  
  C++ Note: risk2 checked 6011.82 0.000944651  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 6489.99  
  C++ Note: risk1r checked 4018.99 0.000575324  
  C++ Note: risk2r checked 4018.99 0.000575324  
  C++ Note: riskl checked 119.492  
  C++ Note: risk1l checked 49.4925 1.62651e-05  
  C++ Note: risk2l checked 49.4925 1.62651e-05  
  C++ Note: df101 -329.891 -329.891  
  C++ Note: df102 -21.7852 9.27193e-06  
  C++ Note: df103 -19.521 9.27193e-06  
  C++ Note: df104 0.01 -15  
  C++ Note: df105 1.11599 1  
  C++ Note: df106 15.1429 -3.55796e+07  
  C++ Note: riskr checked 6489.99  
  C++ Note: risk1r checked 4018.99 0.000575324  
  C++ Note: risk2r checked 4018.99 0.000575324  
  C++ Note: riskl checked 119.492  
  C++ Note: risk1l checked 49.4925 1.62651e-05  
  C++ Note: risk2l checked 49.4925 1.62651e-05  
  C++ Note: df101 -329.891 -329.891  
  C++ Note: df102 -21.7852 9.27193e-06  
  C++ Note: df103 -19.521 9.27193e-06  
  C++ Note: df104 0.01 -15  
  C++ Note: df105 1.11599 1  
  C++ Note: df106 15.1429 -3.55796e+07  
  C++ Note: df501 -329.8914
  C++ Note: df504 0.01 -15  
  Note: 86 risk groups
  C++ Note: START_PLOT
  C++ Note: Current Time, Fri Sep 29 06:00:56 2023
  
  C++ Note: Term checked 0 1  
  C++ Note: df99,92,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:56 2023
  
  C++ Note: values checked 0.01 -15  
  C++ Note: sums checked 6437.95 3328  
  C++ Note: derivs checked 3813.95 0.000939732  
  C++ Note: second derivs checked 3813.95 0.000939732  
  C++ Note: dose checked 6400 6400  
  C++ Note: non-dose checked 6437.95 3328  
  C++ Note: LIN_non-dose checked 6400 6400  
  C++ Note: PLIN_non-dose checked 6400 6400  
  C++ Note: LOGLIN_non-dose checked 6437.95 3328  
  C++ Note: risk checked 9787.82  
  C++ Note: risk1 checked 6011.82 0.000944651  
  C++ Note: risk2 checked 6011.82 0.000944651  
  C++ Note: Grouping Start
  C++ Note: df100 6645 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:56 2023
  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 6489.99  
  C++ Note: risk1r checked 4018.99 0.000575324  
  C++ Note: risk2r checked 4018.99 0.000575324  
  C++ Note: riskl checked 119.492  
  C++ Note: risk1l checked 49.4925 1.62651e-05  
  C++ Note: risk2l checked 49.4925 1.62651e-05  
  C++ Note: df101 -329.891 -329.891  
  C++ Note: df102 -21.7852 9.27193e-06  
  C++ Note: df103 -19.521 9.27193e-06  
  C++ Note: df104 0.01 -15  
  C++ Note: df105 1.11599 1  
  C++ Note: df106 15.1429 -3.55796e+07  
  C++ Note: starting plot data 
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 2 risk groups
  Note: 2 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:00:58 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,83,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:58 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 241 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:58 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.11965  
  C++ Note: risk1r checked 6.27591  
  C++ Note: risk2r checked 39.4822  
  C++ Note: riskl checked 1.11965  
  C++ Note: risk1l checked 6.27591  
  C++ Note: risk2l checked 39.4822  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 1.11965  
  C++ Note: risk1r checked 6.27591  
  C++ Note: risk2r checked 39.4822  
  C++ Note: riskl checked 1.11965  
  C++ Note: risk1l checked 6.27591  
  C++ Note: risk2l checked 39.4822  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: ending guess 0
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1, 0<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.11965  
  C++ Note: risk1r checked 6.27591  
  C++ Note: risk2r checked 39.4822  
  C++ Note: riskl checked 1.11965  
  C++ Note: risk1l checked 6.27591  
  C++ Note: risk2l checked 39.4822  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 1.11965  
  C++ Note: risk1r checked 6.27591  
  C++ Note: risk2r checked 39.4822  
  C++ Note: riskl checked 1.11965  
  C++ Note: risk1l checked 6.27591  
  C++ Note: risk2l checked 39.4822  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  Note: starting ph_plot
  C++ Note: START_PLOT
  C++ Note: Current Time, Fri Sep 29 06:00:58 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,61,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:58 2023
  
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Grouping Start
  C++ Note: df100 517 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:58 2023
  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.11965  
  C++ Note: risk1r checked 6.27591  
  C++ Note: risk2r checked 39.4822  
  C++ Note: riskl checked 1.11965  
  C++ Note: risk1l checked 6.27591  
  C++ Note: risk2l checked 39.4822  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  Note: writing survival data
  Note: Plotting Martingale Residuals
  Note: Martingale Plot: d
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Note: Starting Plot Function
  Note: Getting Plot Info
  Note: 3 risk groups
  Note: 3 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:00:59 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,68,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:59 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 230 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:59 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: ending guess 0
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1, 0<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  C++ Note: df501 0
  C++ Note: df504 -0.1  
  Note: starting ph_plot
  C++ Note: START_PLOT
  C++ Note: Current Time, Fri Sep 29 06:00:59 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,64,Starting
  C++ Note: Current Time, Fri Sep 29 06:00:59 2023
  
  C++ Note: values checked -0.1  
  C++ Note: sums checked 3.91896  
  C++ Note: derivs checked 21.9591  
  C++ Note: second derivs checked 138.335  
  C++ Note: dose checked 7  
  C++ Note: non-dose checked 3.91896  
  C++ Note: LIN_non-dose checked 7  
  C++ Note: PLIN_non-dose checked 7  
  C++ Note: LOGLIN_non-dose checked 3.91896  
  C++ Note: risk checked 3.91896  
  C++ Note: risk1 checked 21.9591  
  C++ Note: risk2 checked 138.335  
  C++ Note: Grouping Start
  C++ Note: df100 576 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:00:59 2023
  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 1.84393  
  C++ Note: risk1r checked 8.73121  
  C++ Note: risk2r checked 46.1633  
  C++ Note: riskl checked 1.84393  
  C++ Note: risk1l checked 8.73121  
  C++ Note: risk2l checked 46.1633  
  C++ Note: df101 0  
  C++ Note: df102 0  
  C++ Note: df103 0  
  C++ Note: df104 -0.1  
  C++ Note: df105 -nan  
  C++ Note: df106 -nan  
  Note: writing survival data
  Note: Plotting Survival Curves
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  Note: Plotting Kaplan-Meier Curve
  Saving 7 x 7 in image
  C++ Error: A non-positive risk was detected: 0
  C++ Warning: final failing values -0.1 0.1 1  
  C++ Error: A non-positive risk was detected: 0
  C++ Warning: final failing values -0.1 0.1 1  
  Saving 7 x 7 in image
  Saving 7 x 7 in image
  0.0104639
  0.0104639
  0.000173242
  0.000173242
  0.0983888
  Error: a0 arguement was negative
  Error: a0 arguement was not a number
  Error: a0 arguement was not a number
  Error: a0 arguement was negative
  Error: a0 arguement was not a number
  Error: a0 arguement was not a number
  Error: a0 arguement was not a number
  Error: goal is too low
  Error: a0 arguement was negative
  Warning: Parameters used: 4, Covariates used: 5, Remaining filled with 0.01
  Error: Atleast one parameter must be free
  Error: Parameters used: 6, Covariates used: 5
  Error: Terms used: 4, Covariates used: 5
  Error: Terms used: 6, Covariates used: 5
  Error: Term types used: 4, Covariates used: 5
  Error: Term types used: 6, Covariates used: 5
  Error: lin_int missing
  Error: step_int missing
  Error: loglin_top missing
  Error: lin_quad_int missing
  Error: lin_exp_int missing
  Error: lin_exp_exp_slope missing
  Error: step_slope missing
  Error: lin_slope missing
  Error: lin_quad_slope missing
  Error: lin_exp_slope missing
  Error: lin_exp_int missing
  Error: Parameters used in first option: 5, Parameters used in different option: 4, please fix parameter length
  Warning: Parameters used: 4, Covariates used: 5, Remaining filled with 0.01
  Error: Parameters used: 6, Covariates used: 5
  Error: Terms used: 4, Covariates used: 5
  Error: Terms used: 6, Covariates used: 5
  Error: Term types used: 4, Covariates used: 5
  Error: Term types used: 6, Covariates used: 5
  C++ Error: A non-positive risk was detected: -0.3510469
  C++ Warning: final failing values -0.1 -0.1 6 0.1  
  C++ Warning: final failing terms loglin lin_exp_slope lin_exp_int lin_exp_exp_slope  
  C++ Error: A non-positive risk was detected: -16.28669
  C++ Warning: final failing values 0.2103257 6.809552 -0.8465196 2.056545  
  C++ Warning: final failing terms loglin lin_exp_slope lin_exp_int lin_exp_exp_slope  
  C++ Error: A non-positive risk was detected: -0.3510469
  C++ Warning: final failing values -0.1 -0.1 6 0.1  
  C++ Warning: final failing terms loglin lin_exp_slope lin_exp_int lin_exp_exp_slope  
  C++ Error: A non-positive risk was detected: -0.3510469
  C++ Warning: final failing values -0.1 -0.1 6 0.1  
  C++ Warning: final failing terms loglin lin_exp_slope lin_exp_int lin_exp_exp_slope  
  C++ Error: A non-positive risk was detected: -2.008635
  C++ Warning: final failing values 0.4557708 6.798468 -0.5625919 1.793063  
  C++ Warning: final failing terms loglin lin_exp_slope lin_exp_int lin_exp_exp_slope  
  Error: Parameters used: 7, Covariates used: 4
  Error: Terms used: 1, Covariates used: 4
  Error: Terms used: 8, Covariates used: 4
  Error: Term types used: 1, Covariates used: 4
  Error: Term types used: 5, Covariates used: 4
  Note: 2  strata used
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 1517 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 3237  
  C++ Note: riskl checked 59  
  Note: 2  strata used
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,69,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 1753 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: Starting Halves
  C++ Note: df501 -447.4645
  C++ Note: df504 0.01  
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: df100 5269 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: ending guess 0
  C++ Note: df501 -447.4645
  C++ Note: df504 0.01  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.01, -447.4645<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: Starting Halves
  C++ Note: df501 -447.4645
  C++ Note: df504 0.01  
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: df100 22449 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: df501 -447.4645
  C++ Note: df504 0.01  
  Note: 2  strata used
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 12944 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 3237  
  C++ Note: riskl checked 59  
  Note: 2  strata used
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,76,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 2073 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df102 -4.51629  
  C++ Note: df103 -38.8061  
  C++ Note: df104 0.01  
  C++ Note: df105 0.116381  
  C++ Note: df106 99.0778  
  C++ Note: Starting Halves
  C++ Note: df501 -447.4645
  C++ Note: df504 0.01  
  C++ Note: values checked -0.0772857  
  C++ Note: sums checked 886.858  
  C++ Note: risk checked 886.858  
  C++ Note: risk1 checked 1314.48  
  C++ Note: risk2 checked 3543.11  
  C++ Note: riskr checked 2906.58 2520.49  
  C++ Note: riskl checked 51.6944 47.43  
  C++ Note: df101 -447.218  
  C++ Note: df102 -1.11664  
  C++ Note: df103 -39.0819  
  C++ Note: df104 -0.0772857  
  C++ Note: df105 0.0285718  
  C++ Note: df106 400.504  
  C++ Note: df100 44602 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 2906.58 2520.49  
  C++ Note: riskl checked 51.6944 47.43  
  C++ Note: df101 -447.218  
  C++ Note: df102 -1.11664  
  C++ Note: df103 -39.0819  
  C++ Note: df104 -0.0772857  
  C++ Note: df105 0.0285718  
  C++ Note: df106 400.504  
  C++ Note: ending guess 0
  C++ Note: df501 -447.2185
  C++ Note: df504 -0.07728569  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.07728569, -447.2185<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.0772857  
  C++ Note: sums checked 886.858  
  C++ Note: risk checked 886.858  
  C++ Note: risk1 checked 1314.48  
  C++ Note: risk2 checked 3543.11  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2906.58 2520.49  
  C++ Note: riskl checked 51.6944 47.43  
  C++ Note: df101 -447.218  
  C++ Note: df102 -1.11664  
  C++ Note: df103 -39.0819  
  C++ Note: df104 -0.0772857  
  C++ Note: df105 0.0285718  
  C++ Note: df106 400.504  
  C++ Note: Starting Halves
  C++ Note: df501 -447.2185
  C++ Note: df504 -0.07728569  
  C++ Note: values checked -0.0987146  
  C++ Note: sums checked 859.484  
  C++ Note: risk checked 859.484  
  C++ Note: risk1 checked 1241.17  
  C++ Note: risk2 checked 3301.92  
  C++ Note: riskr checked 2824.77 2437.74  
  C++ Note: riskl checked 49.9037 45.6007  
  C++ Note: df101 -447.204  
  C++ Note: df102 -0.27852  
  C++ Note: df103 -39.141  
  C++ Note: df104 -0.0987146  
  C++ Note: df105 0.00711582  
  C++ Note: df106 1605.64  
  C++ Note: df100 68658 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 2824.77 2437.74  
  C++ Note: riskl checked 49.9037 45.6007  
  C++ Note: df101 -447.204  
  C++ Note: df102 -0.27852  
  C++ Note: df103 -39.141  
  C++ Note: df104 -0.0987146  
  C++ Note: df105 0.00711582  
  C++ Note: df106 1605.64  
  C++ Note: riskr checked 2824.77 2437.74  
  C++ Note: riskl checked 49.9037 45.6007  
  C++ Note: df101 -447.204  
  C++ Note: df102 -0.27852  
  C++ Note: df103 -39.141  
  C++ Note: df104 -0.0987146  
  C++ Note: df105 0.00711582  
  C++ Note: df106 1605.64  
  C++ Note: df501 -447.2035
  C++ Note: df504 -0.09871455  
  Note: 2  strata used
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 1669 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 3237  
  C++ Note: riskl checked 59  
  Note: 2  strata used
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,69,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 1756 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1016.5  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: Starting Halves
  C++ Note: df501 -447.4645
  C++ Note: df504 0.01  
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1016.5  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: df100 19517 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: ending guess 0
  C++ Note: df501 -447.4645
  C++ Note: df504 0.01  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.01, -447.4645<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1016.5  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: Starting Halves
  C++ Note: df501 -447.4645
  C++ Note: df504 0.01  
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1016.5  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: df100 24694 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df104 0.01  
  C++ Note: df501 -447.4645
  C++ Note: df504 0.01  
  Note: 2  strata used
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 13990 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 3237  
  C++ Note: riskl checked 59  
  Note: 2  strata used
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,61,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 8583 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: derivs checked 1673.67  
  C++ Note: second derivs checked 4753.83  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1016.5  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 3284.26 2905.4  
  C++ Note: riskl checked 60.0534 56.1054  
  C++ Note: df101 -447.464  
  C++ Note: df102 -4.51629  
  C++ Note: df103 -38.8061  
  C++ Note: df104 0.01  
  C++ Note: df105 0.116381  
  C++ Note: df106 99.0778  
  C++ Note: Starting Halves
  C++ Note: df501 -447.4645
  C++ Note: df504 0.01  
  C++ Note: values checked -0.0772857  
  C++ Note: sums checked 886.858  
  C++ Note: derivs checked 1314.48  
  C++ Note: second derivs checked 3543.11  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 886.858  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 886.858  
  C++ Note: risk checked 886.858  
  C++ Note: risk1 checked 1314.48  
  C++ Note: risk2 checked 3543.11  
  C++ Note: riskr checked 2906.58 2520.49  
  C++ Note: riskl checked 51.6944 47.43  
  C++ Note: df101 -447.218  
  C++ Note: df102 -1.11664  
  C++ Note: df103 -39.0819  
  C++ Note: df104 -0.0772857  
  C++ Note: df105 0.0285718  
  C++ Note: df106 400.504  
  C++ Note: df100 28324 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 2906.58 2520.49  
  C++ Note: riskl checked 51.6944 47.43  
  C++ Note: df101 -447.218  
  C++ Note: df102 -1.11664  
  C++ Note: df103 -39.0819  
  C++ Note: df104 -0.0772857  
  C++ Note: df105 0.0285718  
  C++ Note: df106 400.504  
  C++ Note: ending guess 0
  C++ Note: df501 -447.2185
  C++ Note: df504 -0.07728569  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.07728569, -447.2185<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.0772857  
  C++ Note: sums checked 886.858  
  C++ Note: derivs checked 1314.48  
  C++ Note: second derivs checked 3543.11  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 886.858  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 886.858  
  C++ Note: risk checked 886.858  
  C++ Note: risk1 checked 1314.48  
  C++ Note: risk2 checked 3543.11  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2906.58 2520.49  
  C++ Note: riskl checked 51.6944 47.43  
  C++ Note: df101 -447.218  
  C++ Note: df102 -1.11664  
  C++ Note: df103 -39.0819  
  C++ Note: df104 -0.0772857  
  C++ Note: df105 0.0285718  
  C++ Note: df106 400.504  
  C++ Note: Starting Halves
  C++ Note: df501 -447.2185
  C++ Note: df504 -0.07728569  
  C++ Note: values checked -0.0987146  
  C++ Note: sums checked 859.484  
  C++ Note: derivs checked 1241.17  
  C++ Note: second derivs checked 3301.92  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 859.484  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 859.484  
  C++ Note: risk checked 859.484  
  C++ Note: risk1 checked 1241.17  
  C++ Note: risk2 checked 3301.92  
  C++ Note: riskr checked 2824.77 2437.74  
  C++ Note: riskl checked 49.9037 45.6007  
  C++ Note: df101 -447.204  
  C++ Note: df102 -0.27852  
  C++ Note: df103 -39.141  
  C++ Note: df104 -0.0987146  
  C++ Note: df105 0.00711582  
  C++ Note: df106 1605.64  
  C++ Note: df100 48322 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:25 2023
  
  C++ Note: riskr checked 2824.77 2437.74  
  C++ Note: riskl checked 49.9037 45.6007  
  C++ Note: df101 -447.204  
  C++ Note: df102 -0.27852  
  C++ Note: df103 -39.141  
  C++ Note: df104 -0.0987146  
  C++ Note: df105 0.00711582  
  C++ Note: df106 1605.64  
  C++ Note: riskr checked 2824.77 2437.74  
  C++ Note: riskl checked 49.9037 45.6007  
  C++ Note: df101 -447.204  
  C++ Note: df102 -0.27852  
  C++ Note: df103 -39.141  
  C++ Note: df104 -0.0987146  
  C++ Note: df105 0.00711582  
  C++ Note: df106 1605.64  
  C++ Note: df501 -447.2035
  C++ Note: df504 -0.09871455  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 861 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,59,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 8160 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: Starting Halves
  C++ Note: df501 -525.8191
  C++ Note: df504 0.01  
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: df100 10178 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: ending guess 0
  C++ Note: df501 -525.8191
  C++ Note: df504 0.01  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.01, -525.8191<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: Starting Halves
  C++ Note: df501 -525.8191
  C++ Note: df504 0.01  
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: df100 12849 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: df501 -525.8191
  C++ Note: df504 0.01  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 803 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,63,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 936 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12309.1  
  C++ Note: risk1r checked 19240.9  
  C++ Note: risk2r checked 46924.9  
  C++ Note: riskl checked 116.159  
  C++ Note: risk1l checked 218.829  
  C++ Note: risk2l checked 595.535  
  C++ Note: df101 -525.819  
  C++ Note: df102 -4.47019  
  C++ Note: df103 -39.2834  
  C++ Note: df104 0.01  
  C++ Note: df105 0.113793  
  C++ Note: df106 117.628  
  C++ Note: Starting Halves
  C++ Note: df501 -525.8191
  C++ Note: df504 0.01  
  C++ Note: values checked -0.0753449  
  C++ Note: sums checked 889.415  
  C++ Note: risk checked 889.415  
  C++ Note: risk1 checked 1321.38  
  C++ Note: risk2 checked 3565.92  
  C++ Note: riskr checked 10823.9  
  C++ Note: risk1r checked 15714.3  
  C++ Note: risk2r checked 36253.4  
  C++ Note: riskl checked 99.4622  
  C++ Note: risk1l checked 174.499  
  C++ Note: risk2l checked 450.907  
  C++ Note: df101 -525.581  
  C++ Note: df102 -1.10144  
  C++ Note: df103 -39.6548  
  C++ Note: df104 -0.0753449  
  C++ Note: df105 0.0277758  
  C++ Note: df106 477.175  
  C++ Note: df100 5085 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 10823.9  
  C++ Note: risk1r checked 15714.3  
  C++ Note: risk2r checked 36253.4  
  C++ Note: riskl checked 99.4622  
  C++ Note: risk1l checked 174.499  
  C++ Note: risk2l checked 450.907  
  C++ Note: df101 -525.581  
  C++ Note: df102 -1.10144  
  C++ Note: df103 -39.6548  
  C++ Note: df104 -0.0753449  
  C++ Note: df105 0.0277758  
  C++ Note: df106 477.175  
  C++ Note: ending guess 0
  C++ Note: df501 -525.5812
  C++ Note: df504 -0.07534494  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.07534494, -525.5812<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.0753449  
  C++ Note: sums checked 889.415  
  C++ Note: risk checked 889.415  
  C++ Note: risk1 checked 1321.38  
  C++ Note: risk2 checked 3565.92  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 10823.9  
  C++ Note: risk1r checked 15714.3  
  C++ Note: risk2r checked 36253.4  
  C++ Note: riskl checked 99.4622  
  C++ Note: risk1l checked 174.499  
  C++ Note: risk2l checked 450.907  
  C++ Note: df101 -525.581  
  C++ Note: df102 -1.10144  
  C++ Note: df103 -39.6548  
  C++ Note: df104 -0.0753449  
  C++ Note: df105 0.0277758  
  C++ Note: df106 477.175  
  C++ Note: Starting Halves
  C++ Note: df501 -525.5812
  C++ Note: df504 -0.07534494  
  C++ Note: values checked -0.0961768  
  C++ Note: sums checked 862.645  
  C++ Note: risk checked 862.645  
  C++ Note: risk1 checked 1249.59  
  C++ Note: risk2 checked 3329.49  
  C++ Note: riskr checked 10504.3  
  C++ Note: risk1r checked 14981.8  
  C++ Note: risk2r checked 34097.7  
  C++ Note: riskl checked 95.9227  
  C++ Note: risk1l checked 165.411  
  C++ Note: risk2l checked 421.981  
  C++ Note: df101 -525.567  
  C++ Note: df102 -0.274471  
  C++ Note: df103 -39.7399  
  C++ Note: df104 -0.0961768  
  C++ Note: df105 0.00690668  
  C++ Note: df106 1914.84  
  C++ Note: df100 10336 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 10504.3  
  C++ Note: risk1r checked 14981.8  
  C++ Note: risk2r checked 34097.7  
  C++ Note: riskl checked 95.9227  
  C++ Note: risk1l checked 165.411  
  C++ Note: risk2l checked 421.981  
  C++ Note: df101 -525.567  
  C++ Note: df102 -0.274471  
  C++ Note: df103 -39.7399  
  C++ Note: df104 -0.0961768  
  C++ Note: df105 0.00690668  
  C++ Note: df106 1914.84  
  C++ Note: riskr checked 10504.3  
  C++ Note: risk1r checked 14981.8  
  C++ Note: risk2r checked 34097.7  
  C++ Note: riskl checked 95.9227  
  C++ Note: risk1l checked 165.411  
  C++ Note: risk2l checked 421.981  
  C++ Note: df101 -525.567  
  C++ Note: df102 -0.274471  
  C++ Note: df103 -39.7399  
  C++ Note: df104 -0.0961768  
  C++ Note: df105 0.00690668  
  C++ Note: df106 1914.84  
  C++ Note: df501 -525.5668
  C++ Note: df504 -0.09617677  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 853 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,75,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 15893 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1016.5  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: Starting Halves
  C++ Note: df501 -525.8191
  C++ Note: df504 0.01  
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1016.5  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: df100 18081 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: ending guess 0
  C++ Note: df501 -525.8191
  C++ Note: df504 0.01  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.01, -525.8191<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1016.5  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: Starting Halves
  C++ Note: df501 -525.8191
  C++ Note: df504 0.01  
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1016.5  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: df100 21036 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: riskr checked 12309.1  
  C++ Note: riskl checked 116.159  
  C++ Note: df101 -525.819  
  C++ Note: df104 0.01  
  C++ Note: df501 -525.8191
  C++ Note: df504 0.01  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 779 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,79,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 906 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0.01  
  C++ Note: sums checked 1016.5  
  C++ Note: derivs checked 1673.67  
  C++ Note: second derivs checked 4753.83  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1016.5  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1016.5  
  C++ Note: risk checked 1016.5  
  C++ Note: risk1 checked 1673.67  
  C++ Note: risk2 checked 4753.83  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12309.1  
  C++ Note: risk1r checked 19240.9  
  C++ Note: risk2r checked 46924.9  
  C++ Note: riskl checked 116.159  
  C++ Note: risk1l checked 218.829  
  C++ Note: risk2l checked 595.535  
  C++ Note: df101 -525.819  
  C++ Note: df102 -4.47019  
  C++ Note: df103 -39.2834  
  C++ Note: df104 0.01  
  C++ Note: df105 0.113793  
  C++ Note: df106 117.628  
  C++ Note: Starting Halves
  C++ Note: df501 -525.8191
  C++ Note: df504 0.01  
  C++ Note: values checked -0.0753449  
  C++ Note: sums checked 889.415  
  C++ Note: derivs checked 1321.38  
  C++ Note: second derivs checked 3565.92  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 889.415  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 889.415  
  C++ Note: risk checked 889.415  
  C++ Note: risk1 checked 1321.38  
  C++ Note: risk2 checked 3565.92  
  C++ Note: riskr checked 10823.9  
  C++ Note: risk1r checked 15714.3  
  C++ Note: risk2r checked 36253.4  
  C++ Note: riskl checked 99.4622  
  C++ Note: risk1l checked 174.499  
  C++ Note: risk2l checked 450.907  
  C++ Note: df101 -525.581  
  C++ Note: df102 -1.10144  
  C++ Note: df103 -39.6548  
  C++ Note: df104 -0.0753449  
  C++ Note: df105 0.0277758  
  C++ Note: df106 477.175  
  C++ Note: df100 5211 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 10823.9  
  C++ Note: risk1r checked 15714.3  
  C++ Note: risk2r checked 36253.4  
  C++ Note: riskl checked 99.4622  
  C++ Note: risk1l checked 174.499  
  C++ Note: risk2l checked 450.907  
  C++ Note: df101 -525.581  
  C++ Note: df102 -1.10144  
  C++ Note: df103 -39.6548  
  C++ Note: df104 -0.0753449  
  C++ Note: df105 0.0277758  
  C++ Note: df106 477.175  
  C++ Note: ending guess 0
  C++ Note: df501 -525.5812
  C++ Note: df504 -0.07534494  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.07534494, -525.5812<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.0753449  
  C++ Note: sums checked 889.415  
  C++ Note: derivs checked 1321.38  
  C++ Note: second derivs checked 3565.92  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 889.415  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 889.415  
  C++ Note: risk checked 889.415  
  C++ Note: risk1 checked 1321.38  
  C++ Note: risk2 checked 3565.92  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 10823.9  
  C++ Note: risk1r checked 15714.3  
  C++ Note: risk2r checked 36253.4  
  C++ Note: riskl checked 99.4622  
  C++ Note: risk1l checked 174.499  
  C++ Note: risk2l checked 450.907  
  C++ Note: df101 -525.581  
  C++ Note: df102 -1.10144  
  C++ Note: df103 -39.6548  
  C++ Note: df104 -0.0753449  
  C++ Note: df105 0.0277758  
  C++ Note: df106 477.175  
  C++ Note: Starting Halves
  C++ Note: df501 -525.5812
  C++ Note: df504 -0.07534494  
  C++ Note: values checked -0.0961768  
  C++ Note: sums checked 862.645  
  C++ Note: derivs checked 1249.59  
  C++ Note: second derivs checked 3329.49  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 862.645  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 862.645  
  C++ Note: risk checked 862.645  
  C++ Note: risk1 checked 1249.59  
  C++ Note: risk2 checked 3329.49  
  C++ Note: riskr checked 10504.3  
  C++ Note: risk1r checked 14981.8  
  C++ Note: risk2r checked 34097.7  
  C++ Note: riskl checked 95.9227  
  C++ Note: risk1l checked 165.411  
  C++ Note: risk2l checked 421.981  
  C++ Note: df101 -525.567  
  C++ Note: df102 -0.274471  
  C++ Note: df103 -39.7399  
  C++ Note: df104 -0.0961768  
  C++ Note: df105 0.00690668  
  C++ Note: df106 1914.84  
  C++ Note: df100 47294 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 10504.3  
  C++ Note: risk1r checked 14981.8  
  C++ Note: risk2r checked 34097.7  
  C++ Note: riskl checked 95.9227  
  C++ Note: risk1l checked 165.411  
  C++ Note: risk2l checked 421.981  
  C++ Note: df101 -525.567  
  C++ Note: df102 -0.274471  
  C++ Note: df103 -39.7399  
  C++ Note: df104 -0.0961768  
  C++ Note: df105 0.00690668  
  C++ Note: df106 1914.84  
  C++ Note: riskr checked 10504.3  
  C++ Note: risk1r checked 14981.8  
  C++ Note: risk2r checked 34097.7  
  C++ Note: riskl checked 95.9227  
  C++ Note: risk1l checked 165.411  
  C++ Note: risk2l checked 421.981  
  C++ Note: df101 -525.567  
  C++ Note: df102 -0.274471  
  C++ Note: df103 -39.7399  
  C++ Note: df104 -0.0961768  
  C++ Note: df105 0.00690668  
  C++ Note: df106 1914.84  
  C++ Note: df501 -525.5668
  C++ Note: df504 -0.09617677  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,57,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 858 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0  
  C++ Note: sums checked 1000  
  C++ Note: derivs checked 1626.94  
  C++ Note: second derivs checked 4593.87  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1000  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: risk1 checked 1626.94  
  C++ Note: risk2 checked 4593.87  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: ending guess 0
  C++ Note: df501 -525.7764
  C++ Note: df504 0  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0, -525.7764<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0  
  C++ Note: sums checked 1000  
  C++ Note: derivs checked 1626.94  
  C++ Note: second derivs checked 4593.87  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1000  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: risk1 checked 1626.94  
  C++ Note: risk2 checked 4593.87  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: df501 -525.7764
  C++ Note: df504 0  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 788 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,64,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 953 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0  
  C++ Note: sums checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: risk1 checked 1626.94  
  C++ Note: risk2 checked 4593.87  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  C++ Note: df101 -525.776  
  C++ Note: df104 0  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  C++ Note: df101 -525.776  
  C++ Note: df104 0  
  C++ Note: ending guess 0
  C++ Note: df501 -525.7764
  C++ Note: df504 0  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0, -525.7764<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0  
  C++ Note: sums checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: risk1 checked 1626.94  
  C++ Note: risk2 checked 4593.87  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  C++ Note: df101 -525.776  
  C++ Note: df104 0  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  C++ Note: df101 -525.776  
  C++ Note: df104 0  
  C++ Note: df501 -525.7764
  C++ Note: df504 0  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 865 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,84,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 970 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0  
  C++ Note: sums checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: risk1 checked 1626.94  
  C++ Note: risk2 checked 4593.87  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: ending guess 0
  C++ Note: df501 -525.7764
  C++ Note: df504 0  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0, -525.7764<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0  
  C++ Note: sums checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: risk1 checked 1626.94  
  C++ Note: risk2 checked 4593.87  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: df501 -525.7764
  C++ Note: df504 0  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 809 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,67,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 935 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0  
  C++ Note: sums checked 1000  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1000  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  C++ Note: df101 -525.776  
  C++ Note: df104 0  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  C++ Note: df101 -525.776  
  C++ Note: df104 0  
  C++ Note: ending guess 0
  C++ Note: df501 -525.7764
  C++ Note: df504 0  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0, -525.7764<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0  
  C++ Note: sums checked 1000  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1000  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  C++ Note: df101 -525.776  
  C++ Note: df104 0  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  C++ Note: df101 -525.776  
  C++ Note: df104 0  
  C++ Note: df501 -525.7764
  C++ Note: df504 0  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 876 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:26 2023
  
  C++ Note: riskr checked 12119  
  C++ Note: riskl checked 114  
  Note: 114 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: Term checked 0  
  C++ Note: df99,67,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 1153 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0  
  C++ Note: sums checked 1000  
  C++ Note: derivs checked 1626.94  
  C++ Note: second derivs checked 4593.87  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1000  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: risk1 checked 1626.94  
  C++ Note: risk2 checked 4593.87  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: ending guess 0
  C++ Note: df501 -525.7764
  C++ Note: df504 0  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0, -525.7764<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0  
  C++ Note: sums checked 1000  
  C++ Note: derivs checked 1626.94  
  C++ Note: second derivs checked 4593.87  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1000  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: risk1 checked 1626.94  
  C++ Note: risk2 checked 4593.87  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: riskr checked 12119  
  C++ Note: risk1r checked 18778.8  
  C++ Note: risk2r checked 45501.3  
  C++ Note: riskl checked 114  
  C++ Note: risk1l checked 212.971  
  C++ Note: risk2l checked 576.121  
  C++ Note: df101 -525.776  
  C++ Note: df102 -4.07712  
  C++ Note: df103 -39.3287  
  C++ Note: df104 0  
  C++ Note: df105 0.103668  
  C++ Note: df106 128.958  
  C++ Note: df501 -525.7764
  C++ Note: df504 0  
  Note: 901 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,74,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 5679 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked 0 0  
  C++ Note: sums checked 1000 1000  
  C++ Note: derivs checked 531  
  C++ Note: second derivs checked 531  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1000  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: risk1 checked 531  
  C++ Note: risk2 checked 531  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 94828  
  C++ Note: risk1r checked 50387  
  C++ Note: risk2r checked 50387  
  C++ Note: riskl checked 901  
  C++ Note: risk1l checked 479  
  C++ Note: risk2l checked 479  
  C++ Note: df101 -4115.03  
  C++ Note: df102 1.62  
  C++ Note: df103 -222.912  
  C++ Note: df104 0 0  
  C++ Note: df105 -0.00726744  
  C++ Note: df106 -2540.14  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.028
  C++ Note: df504 0 0  
  C++ Note: values checked 0 0.00545058  
  C++ Note: sums checked 1000 1002.9  
  C++ Note: derivs checked 533.902  
  C++ Note: second derivs checked 533.902  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1002.9  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1002.9  
  C++ Note: risk checked 1002.9  
  C++ Note: risk1 checked 533.902  
  C++ Note: risk2 checked 533.902  
  C++ Note: riskr checked 95103.4  
  C++ Note: risk1r checked 50662.4  
  C++ Note: risk2r checked 50662.4  
  C++ Note: riskl checked 903.618  
  C++ Note: risk1l checked 481.618  
  C++ Note: risk2l checked 481.618  
  C++ Note: df101 -8230.04  
  C++ Note: df102 0.810424  
  C++ Note: df103 -445.668  
  C++ Note: df104 0 0.00545058  
  C++ Note: df105 -0.00181845  
  C++ Note: df106 -10155.2  
  C++ Note: df100 62361 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: values checked 0 0.00272529  
  C++ Note: sums checked 1000 1001.45  
  C++ Note: derivs checked 532.449  
  C++ Note: second derivs checked 532.449  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1001.45  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1001.45  
  C++ Note: risk checked 1001.45  
  C++ Note: risk1 checked 532.449  
  C++ Note: risk2 checked 532.449  
  C++ Note: riskr checked 94965.5  
  C++ Note: risk1r checked 50524.5  
  C++ Note: risk2r checked 50524.5  
  C++ Note: riskl checked 902.307  
  C++ Note: risk1l checked 480.307  
  C++ Note: risk2l checked 480.307  
  C++ Note: df101 -8230.05  
  C++ Note: df102 2.02511  
  C++ Note: df103 -445.747  
  C++ Note: df104 0 0.00272529  
  C++ Note: df105 -0.00454318  
  C++ Note: df106 -4064.01  
  C++ Note: df100 98374 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: values checked 0 0.00136265  
  C++ Note: sums checked 1000 1000.72  
  C++ Note: derivs checked 531.724  
  C++ Note: second derivs checked 531.724  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1000.72  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1000.72  
  C++ Note: risk checked 1000.72  
  C++ Note: risk1 checked 531.724  
  C++ Note: risk2 checked 531.724  
  C++ Note: riskr checked 94896.7  
  C++ Note: risk1r checked 50455.7  
  C++ Note: risk2r checked 50455.7  
  C++ Note: riskl checked 901.653  
  C++ Note: risk1l checked 479.653  
  C++ Note: risk2l checked 479.653  
  C++ Note: df101 -4115.03  
  C++ Note: df102 1.31626  
  C++ Note: df103 -222.893  
  C++ Note: df104 0 0.00136265  
  C++ Note: df105 -0.00590537  
  C++ Note: df106 -3126.29  
  C++ Note: df100 123933 3 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 94896.7  
  C++ Note: risk1r checked 50455.7  
  C++ Note: risk2r checked 50455.7  
  C++ Note: riskl checked 901.653  
  C++ Note: risk1l checked 479.653  
  C++ Note: risk2l checked 479.653  
  C++ Note: df101 -4115.03  
  C++ Note: df102 1.31626  
  C++ Note: df103 -222.893  
  C++ Note: df104 0 0.00136265  
  C++ Note: df105 -0.00590537  
  C++ Note: df106 -3126.29  
  C++ Note: ending guess 0
  C++ Note: df501 -4115.026
  C++ Note: df504 0 0.001362646  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0 0.001362646, -4115.026<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0 0.00136265  
  C++ Note: sums checked 1000 1000.72  
  C++ Note: derivs checked 531.724  
  C++ Note: second derivs checked 531.724  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1000.72  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1000.72  
  C++ Note: risk checked 1000.72  
  C++ Note: risk1 checked 531.724  
  C++ Note: risk2 checked 531.724  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 94896.7  
  C++ Note: risk1r checked 50455.7  
  C++ Note: risk2r checked 50455.7  
  C++ Note: riskl checked 901.653  
  C++ Note: risk1l checked 479.653  
  C++ Note: risk2l checked 479.653  
  C++ Note: df101 -4115.03  
  C++ Note: df102 1.31626  
  C++ Note: df103 -222.893  
  C++ Note: df104 0 0.00136265  
  C++ Note: df105 -0.00590537  
  C++ Note: df106 -3126.29  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.026
  C++ Note: df504 0 0.001362646  
  C++ Note: values checked 0 0.00579167  
  C++ Note: sums checked 1000 1003.08  
  C++ Note: derivs checked 534.084  
  C++ Note: second derivs checked 534.084  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.08  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.08  
  C++ Note: risk checked 1003.08  
  C++ Note: risk1 checked 534.084  
  C++ Note: risk2 checked 534.084  
  C++ Note: riskr checked 95120.7  
  C++ Note: risk1r checked 50679.7  
  C++ Note: risk2r checked 50679.7  
  C++ Note: riskl checked 903.782  
  C++ Note: risk1l checked 481.782  
  C++ Note: risk2l checked 481.782  
  C++ Note: df101 -4115.02  
  C++ Note: df102 0.329207  
  C++ Note: df103 -222.829  
  C++ Note: df104 0 0.00579167  
  C++ Note: df105 -0.0014774  
  C++ Note: df106 -12499.8  
  C++ Note: df100 207157 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95120.7  
  C++ Note: risk1r checked 50679.7  
  C++ Note: risk2r checked 50679.7  
  C++ Note: riskl checked 903.782  
  C++ Note: risk1l checked 481.782  
  C++ Note: risk2l checked 481.782  
  C++ Note: df101 -4115.02  
  C++ Note: df102 0.329207  
  C++ Note: df103 -222.829  
  C++ Note: df104 0 0.00579167  
  C++ Note: df105 -0.0014774  
  C++ Note: df106 -12499.8  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.005791671  
  C++ Note: values checked 0 0.00689972  
  C++ Note: sums checked 1000 1003.68  
  C++ Note: derivs checked 534.676  
  C++ Note: second derivs checked 534.676  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.68  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.68  
  C++ Note: risk checked 1003.68  
  C++ Note: risk1 checked 534.676  
  C++ Note: risk2 checked 534.676  
  C++ Note: riskr checked 95176.9  
  C++ Note: risk1r checked 50735.9  
  C++ Note: risk2r checked 50735.9  
  C++ Note: riskl checked 904.316  
  C++ Note: risk1l checked 482.316  
  C++ Note: risk2l checked 482.316  
  C++ Note: df101 -4115.02  
  C++ Note: df102 0.0823107  
  C++ Note: df103 -222.813  
  C++ Note: df104 0 0.00689972  
  C++ Note: df105 -0.000369417  
  C++ Note: df106 -49993.7  
  C++ Note: df100 241374 1 2 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95176.9  
  C++ Note: risk1r checked 50735.9  
  C++ Note: risk2r checked 50735.9  
  C++ Note: riskl checked 904.316  
  C++ Note: risk1l checked 482.316  
  C++ Note: risk2l checked 482.316  
  C++ Note: df101 -4115.02  
  C++ Note: df102 0.0823107  
  C++ Note: df103 -222.813  
  C++ Note: df104 0 0.00689972  
  C++ Note: df105 -0.000369417  
  C++ Note: df106 -49993.7  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.006899718  
  C++ Note: values checked 0 0.00717678  
  C++ Note: sums checked 1000 1003.82  
  C++ Note: derivs checked 534.825  
  C++ Note: second derivs checked 534.825  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.82  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.82  
  C++ Note: risk checked 1003.82  
  C++ Note: risk1 checked 534.825  
  C++ Note: risk2 checked 534.825  
  C++ Note: riskr checked 95190.9  
  C++ Note: risk1r checked 50749.9  
  C++ Note: risk2r checked 50749.9  
  C++ Note: riskl checked 904.45  
  C++ Note: risk1l checked 482.45  
  C++ Note: risk2l checked 482.45  
  C++ Note: df101 -4115.02  
  C++ Note: df102 0.0205783  
  C++ Note: df103 -222.809  
  C++ Note: df104 0 0.00717678  
  C++ Note: df105 -9.23585e-05  
  C++ Note: df106 -199969  
  C++ Note: df100 261751 1 3 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95190.9  
  C++ Note: risk1r checked 50749.9  
  C++ Note: risk2r checked 50749.9  
  C++ Note: riskl checked 904.45  
  C++ Note: risk1l checked 482.45  
  C++ Note: risk2l checked 482.45  
  C++ Note: df101 -4115.02  
  C++ Note: df102 0.0205783  
  C++ Note: df103 -222.809  
  C++ Note: df104 0 0.00717678  
  C++ Note: df105 -9.23585e-05  
  C++ Note: df106 -199969  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007176781  
  C++ Note: values checked 0 0.00724605  
  C++ Note: sums checked 1000 1003.86  
  C++ Note: derivs checked 534.862  
  C++ Note: second derivs checked 534.862  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.86  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.86  
  C++ Note: risk checked 1003.86  
  C++ Note: risk1 checked 534.862  
  C++ Note: risk2 checked 534.862  
  C++ Note: riskr checked 95194.4  
  C++ Note: risk1r checked 50753.4  
  C++ Note: risk2r checked 50753.4  
  C++ Note: riskl checked 904.483  
  C++ Note: risk1l checked 482.483  
  C++ Note: risk2l checked 482.483  
  C++ Note: df101 -4115.02  
  C++ Note: df102 0.0051446  
  C++ Note: df103 -222.808  
  C++ Note: df104 0 0.00724605  
  C++ Note: df105 -2.30899e-05  
  C++ Note: df106 -799872  
  C++ Note: df100 281431 1 4 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95194.4  
  C++ Note: risk1r checked 50753.4  
  C++ Note: risk2r checked 50753.4  
  C++ Note: riskl checked 904.483  
  C++ Note: risk1l checked 482.483  
  C++ Note: risk2l checked 482.483  
  C++ Note: df101 -4115.02  
  C++ Note: df102 0.0051446  
  C++ Note: df103 -222.808  
  C++ Note: df104 0 0.00724605  
  C++ Note: df105 -2.30899e-05  
  C++ Note: df106 -799872  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.00724605  
  C++ Note: values checked 0 0.00726337  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.871  
  C++ Note: second derivs checked 534.871  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.871  
  C++ Note: risk2 checked 534.871  
  C++ Note: riskr checked 95195.3  
  C++ Note: risk1r checked 50754.3  
  C++ Note: risk2r checked 50754.3  
  C++ Note: riskl checked 904.492  
  C++ Note: risk1l checked 482.492  
  C++ Note: risk2l checked 482.492  
  C++ Note: df101 -4115.02  
  C++ Note: df102 0.00128615  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726337  
  C++ Note: df105 -5.77249e-06  
  C++ Note: df106 -3.19948e+06  
  C++ Note: df100 301573 1 5 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95195.3  
  C++ Note: risk1r checked 50754.3  
  C++ Note: risk2r checked 50754.3  
  C++ Note: riskl checked 904.492  
  C++ Note: risk1l checked 482.492  
  C++ Note: risk2l checked 482.492  
  C++ Note: df101 -4115.02  
  C++ Note: df102 0.00128615  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726337  
  C++ Note: df105 -5.77249e-06  
  C++ Note: df106 -3.19948e+06  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007263367  
  C++ Note: values checked 0 0.0072677  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.873  
  C++ Note: second derivs checked 534.873  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.873  
  C++ Note: risk2 checked 534.873  
  C++ Note: riskr checked 95195.5  
  C++ Note: risk1r checked 50754.5  
  C++ Note: risk2r checked 50754.5  
  C++ Note: riskl checked 904.494  
  C++ Note: risk1l checked 482.494  
  C++ Note: risk2l checked 482.494  
  C++ Note: df101 -4115.02  
  C++ Note: df102 0.000321538  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.0072677  
  C++ Note: df105 -1.44312e-06  
  C++ Note: df106 -1.27979e+07  
  C++ Note: df100 346158 1 6 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95195.5  
  C++ Note: risk1r checked 50754.5  
  C++ Note: risk2r checked 50754.5  
  C++ Note: riskl checked 904.494  
  C++ Note: risk1l checked 482.494  
  C++ Note: risk2l checked 482.494  
  C++ Note: df101 -8230.04  
  C++ Note: df102 0.000643076  
  C++ Note: df103 -445.614  
  C++ Note: df104 0 0.0072677  
  C++ Note: df105 -1.44312e-06  
  C++ Note: df106 -1.27979e+07  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007263367  
  C++ Note: values checked 0 0.00726878  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.494  
  C++ Note: risk1l checked 482.494  
  C++ Note: risk2l checked 482.494  
  C++ Note: df101 -4115.02  
  C++ Note: df102 8.03845e-05  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726878  
  C++ Note: df105 -3.60781e-07  
  C++ Note: df106 -5.11917e+07  
  C++ Note: df100 376054 1 7 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.494  
  C++ Note: risk1l checked 482.494  
  C++ Note: risk2l checked 482.494  
  C++ Note: df101 -4115.02  
  C++ Note: df102 8.03845e-05  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726878  
  C++ Note: df105 -3.60781e-07  
  C++ Note: df106 -5.11917e+07  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007268779  
  C++ Note: values checked 0 0.00726905  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -8230.04  
  C++ Note: df102 4.01923e-05  
  C++ Note: df103 -445.614  
  C++ Note: df104 0 0.00726905  
  C++ Note: df105 -9.01952e-08  
  C++ Note: df106 -2.04767e+08  
  C++ Note: df100 426371 1 8 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: values checked 0 0.00726891  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.494  
  C++ Note: risk1l checked 482.494  
  C++ Note: risk2l checked 482.494  
  C++ Note: df101 -8230.04  
  C++ Note: df102 0.000100481  
  C++ Note: df103 -445.614  
  C++ Note: df104 0 0.00726891  
  C++ Note: df105 -2.25488e-07  
  C++ Note: df106 -8.19067e+07  
  C++ Note: df100 450404 2 8 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: values checked 0 0.00726885  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.494  
  C++ Note: risk1l checked 482.494  
  C++ Note: risk2l checked 482.494  
  C++ Note: df101 -4115.02  
  C++ Note: df102 6.53124e-05  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726885  
  C++ Note: df105 -2.93134e-07  
  C++ Note: df106 -6.30052e+07  
  C++ Note: df100 460860 3 8 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.494  
  C++ Note: risk1l checked 482.494  
  C++ Note: risk2l checked 482.494  
  C++ Note: df101 -4115.02  
  C++ Note: df102 6.53124e-05  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726885  
  C++ Note: df105 -2.93134e-07  
  C++ Note: df106 -6.30052e+07  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007268847  
  C++ Note: values checked 0 0.00726907  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.63281e-05  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726907  
  C++ Note: df105 -7.32836e-08  
  C++ Note: df106 -2.52021e+08  
  C++ Note: df100 527695 1 9 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.63281e-05  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726907  
  C++ Note: df105 -7.32836e-08  
  C++ Note: df106 -2.52021e+08  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007269066  
  C++ Note: values checked 0 0.00726912  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 4.08203e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726912  
  C++ Note: df105 -1.83209e-08  
  C++ Note: df106 -1.00808e+09  
  C++ Note: df100 547885 1 10 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: values checked 0 0.00726909  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.02051e-05  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726909  
  C++ Note: df105 -4.58022e-08  
  C++ Note: df106 -4.03233e+08  
  C++ Note: df100 563675 2 10 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.02051e-05  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726909  
  C++ Note: df105 -4.58022e-08  
  C++ Note: df106 -4.03233e+08  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007269094  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 2.55127e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -1.14506e-08  
  C++ Note: df106 -1.61293e+09  
  C++ Note: df100 591227 1 11 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -8230.04  
  C++ Note: df102 5.10253e-06  
  C++ Note: df103 -445.614  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -1.14506e-08  
  C++ Note: df106 -1.61293e+09  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007269094  
  C++ Note: values checked 0 0.00726914  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 6.37817e-07  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726914  
  C++ Note: df105 -2.86264e-09  
  C++ Note: df106 -6.45173e+09  
  C++ Note: df100 638162 1 12 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -8230.04  
  C++ Note: df102 3.18908e-06  
  C++ Note: df103 -445.614  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -7.1566e-09  
  C++ Note: df106 -2.58069e+09  
  C++ Note: df100 658362 2 12 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 2.0729e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -9.30358e-09  
  C++ Note: df106 -1.98515e+09  
  C++ Note: df100 678152 3 12 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 2.31209e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -1.03771e-08  
  C++ Note: df106 -1.77979e+09  
  C++ Note: df100 688258 4 12 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 2.43168e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -1.09138e-08  
  C++ Note: df106 -1.69226e+09  
  C++ Note: df100 698368 5 12 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: Changing back to best
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 2.55127e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -1.14506e-08  
  C++ Note: df106 -1.61293e+09  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007269094  
  C++ Note: values checked 0 0.00726914  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 6.37817e-07  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726914  
  C++ Note: df105 -2.86264e-09  
  C++ Note: df106 -6.45173e+09  
  C++ Note: df100 719086 1 13 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.59454e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -7.1566e-09  
  C++ Note: df106 -2.58069e+09  
  C++ Note: df100 730572 2 13 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:27 2023
  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.59454e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -7.1566e-09  
  C++ Note: df106 -2.58069e+09  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007269133  
  C++ Note: values checked 0 0.00726914  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 3.98635e-07  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726914  
  C++ Note: df105 -1.78915e-09  
  C++ Note: df106 -1.03228e+10  
  C++ Note: df100 750270 1 14 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726914  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 9.96589e-07  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726914  
  C++ Note: df105 -4.47288e-09  
  C++ Note: df106 -4.12911e+09  
  C++ Note: df100 759953 2 14 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.29557e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -5.81474e-09  
  C++ Note: df106 -3.17624e+09  
  C++ Note: df100 771719 3 14 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.44505e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -6.48567e-09  
  C++ Note: df106 -2.84766e+09  
  C++ Note: df100 782324 4 14 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.5198e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -6.82114e-09  
  C++ Note: df106 -2.70761e+09  
  C++ Note: df100 791676 5 14 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: Changing back to best
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.59454e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -7.1566e-09  
  C++ Note: df106 -2.58069e+09  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007269133  
  C++ Note: values checked 0 0.00726914  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 3.98635e-07  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726914  
  C++ Note: df105 -1.78915e-09  
  C++ Note: df106 -1.03228e+10  
  C++ Note: df100 812894 1 15 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726914  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 9.96589e-07  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726914  
  C++ Note: df105 -4.47288e-09  
  C++ Note: df106 -4.12911e+09  
  C++ Note: df100 822915 2 15 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.29557e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -5.81474e-09  
  C++ Note: df106 -3.17624e+09  
  C++ Note: df100 833089 3 15 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.44505e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -6.48567e-09  
  C++ Note: df106 -2.84766e+09  
  C++ Note: df100 843378 4 15 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.5198e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -6.82114e-09  
  C++ Note: df106 -2.70761e+09  
  C++ Note: df100 852937 5 15 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: Changing back to best
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.59454e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -7.1566e-09  
  C++ Note: df106 -2.58069e+09  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007269133  
  C++ Note: values checked 0 0.00726914  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 3.98635e-07  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726914  
  C++ Note: df105 -1.78915e-09  
  C++ Note: df106 -1.03228e+10  
  C++ Note: df100 871824 1 16 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726914  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 9.96589e-07  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726914  
  C++ Note: df105 -4.47288e-09  
  C++ Note: df106 -4.12911e+09  
  C++ Note: df100 902160 2 16 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.29557e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -5.81474e-09  
  C++ Note: df106 -3.17624e+09  
  C++ Note: df100 922153 3 16 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.44505e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -6.48567e-09  
  C++ Note: df106 -2.84766e+09  
  C++ Note: df100 942161 4 16 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -8230.04  
  C++ Note: df102 3.0396e-06  
  C++ Note: df103 -445.614  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -6.82114e-09  
  C++ Note: df106 -2.70761e+09  
  C++ Note: df100 962418 5 16 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: Changing back to best
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.59454e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -7.1566e-09  
  C++ Note: df106 -2.58069e+09  
  C++ Note: Starting Halves
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007269133  
  C++ Note: values checked 0 0.00726914  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 3.98635e-07  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726914  
  C++ Note: df105 -1.78915e-09  
  C++ Note: df106 -1.03228e+10  
  C++ Note: df100 1002153 1 17 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726914  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -8230.04  
  C++ Note: df102 1.99318e-06  
  C++ Note: df103 -445.614  
  C++ Note: df104 0 0.00726914  
  C++ Note: df105 -4.47288e-09  
  C++ Note: df106 -4.12911e+09  
  C++ Note: df100 1022409 2 17 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.29557e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -5.81474e-09  
  C++ Note: df106 -3.17624e+09  
  C++ Note: df100 1038147 3 17 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.44505e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -6.48567e-09  
  C++ Note: df106 -2.84766e+09  
  C++ Note: df100 1060632 4 17 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.5198e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -6.82114e-09  
  C++ Note: df106 -2.70761e+09  
  C++ Note: df100 1086516 5 17 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: Changing back to best
  C++ Note: values checked 0 0.00726913  
  C++ Note: sums checked 1000 1003.87  
  C++ Note: derivs checked 534.874  
  C++ Note: second derivs checked 534.874  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1003.87  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1003.87  
  C++ Note: risk checked 1003.87  
  C++ Note: risk1 checked 534.874  
  C++ Note: risk2 checked 534.874  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -8230.04  
  C++ Note: df102 3.18908e-06  
  C++ Note: df103 -445.614  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -7.1566e-09  
  C++ Note: df106 -2.58069e+09  
  C++ Note: riskr checked 95195.6  
  C++ Note: risk1r checked 50754.6  
  C++ Note: risk2r checked 50754.6  
  C++ Note: riskl checked 904.495  
  C++ Note: risk1l checked 482.495  
  C++ Note: risk2l checked 482.495  
  C++ Note: df101 -4115.02  
  C++ Note: df102 1.59454e-06  
  C++ Note: df103 -222.807  
  C++ Note: df104 0 0.00726913  
  C++ Note: df105 -7.1566e-09  
  C++ Note: df106 -2.58069e+09  
  C++ Note: df501 -4115.022
  C++ Note: df504 0 0.007269133  
  C++ Note: START_PLOT
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,77,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: values checked 0 0  
  C++ Note: sums checked 1000 1000  
  C++ Note: derivs checked 531  
  C++ Note: second derivs checked 531  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 1000  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 1000  
  C++ Note: risk checked 1000  
  C++ Note: risk1 checked 531  
  C++ Note: risk2 checked 531  
  C++ Note: Grouping Start
  C++ Note: df100 15410 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:28 2023
  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 94828  
  C++ Note: risk1r checked 50387  
  C++ Note: risk2r checked 50387  
  C++ Note: riskl checked 901  
  C++ Note: risk1l checked 479  
  C++ Note: risk2l checked 479  
  C++ Note: df101 -8230.06  
  C++ Note: df102 3.24  
  C++ Note: df103 -445.824  
  C++ Note: df104 0 0  
  C++ Note: df105 -0.00726744  
  C++ Note: df106 -2540.14  
  Saving 7 x 7 in image
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,61,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 750 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 3583 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 5122 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -81.64684<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 19376 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 20915 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,78,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 800 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 3993 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 14756 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -81.64684<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 19179 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 20714 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,74,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 14018 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 35528 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -157.492 -157.492  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 54103 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -78.74604<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 76882 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 78393 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,77,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 778 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 3815 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:29 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 21286 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -78.74604<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 25524 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 26998 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -157.492 -157.492  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,64,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 735 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df102 20.2568 3.06352  
  C++ Note: df103 -19.2883 -6.30273  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -1.05021 -0.486062  
  C++ Note: df106 -4.03059 -26.6514  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.71116 0.38487  
  C++ Note: sums checked 5931.55 1249.26  
  C++ Note: risk checked 7349.12  
  C++ Note: risk1 checked 24395.8 4437.37  
  C++ Note: risk2 checked 97505.9 4437.37  
  C++ Note: riskr checked 435.702 565.97 827.445 534.224 709.522  
  C++ Note: riskl checked 41.2127 50.5438 60.5747 34.7714 53.678  
  C++ Note: df101 -70.439 -70.439  
  C++ Note: df102 5.59432 0.70352  
  C++ Note: df103 -15.9304 -6.09947  
  C++ Note: df104 0.71116 0.38487  
  C++ Note: df105 -0.351173 -0.115341  
  C++ Note: df106 -12.5912 -100.124  
  C++ Note: df100 18636 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 435.702 565.97 827.445 534.224 709.522  
  C++ Note: riskl checked 41.2127 50.5438 60.5747 34.7714 53.678  
  C++ Note: df101 -70.439 -70.439  
  C++ Note: df102 5.59432 0.70352  
  C++ Note: df103 -15.9304 -6.09947  
  C++ Note: df104 0.71116 0.38487  
  C++ Note: df105 -0.351173 -0.115341  
  C++ Note: df106 -12.5912 -100.124  
  C++ Note: ending guess 0
  C++ Note: df501 -70.43896
  C++ Note: df504 0.7111601 0.3848703  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.7111601 0.3848703, -70.43896<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.71116 0.38487  
  C++ Note: sums checked 5931.55 1249.26  
  C++ Note: risk checked 7349.12  
  C++ Note: risk1 checked 24395.8 4437.37  
  C++ Note: risk2 checked 97505.9 4437.37  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 435.702 565.97 827.445 534.224 709.522  
  C++ Note: riskl checked 41.2127 50.5438 60.5747 34.7714 53.678  
  C++ Note: df101 -70.439 -70.439  
  C++ Note: df102 5.59432 0.70352  
  C++ Note: df103 -15.9304 -6.09947  
  C++ Note: df104 0.71116 0.38487  
  C++ Note: df105 -0.351173 -0.115341  
  C++ Note: df106 -12.5912 -100.124  
  C++ Note: Starting Halves
  C++ Note: df501 -70.43896
  C++ Note: df504 0.7111601 0.3848703  
  C++ Note: values checked 0.980196 0.504575  
  C++ Note: sums checked 15702.5 1348.49  
  C++ Note: risk checked 20865.8  
  C++ Note: risk1 checked 80872.8 13030.7  
  C++ Note: risk2 checked 352964 13030.7  
  C++ Note: riskr checked 1069.02 1452.99 1849.81 1085.84 1647.1  
  C++ Note: riskl checked 115.522 153.689 150.489 68.5171 156.326  
  C++ Note: df101 -69.4154 -69.4154  
  C++ Note: df102 1.73207 0.18254  
  C++ Note: df103 -13.4724 -5.96434  
  C++ Note: df104 0.980196 0.504575  
  C++ Note: df105 -0.128564 -0.0306052  
  C++ Note: df106 -40.0765 -380.276  
  C++ Note: df100 27315 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 1069.02 1452.99 1849.81 1085.84 1647.1  
  C++ Note: riskl checked 115.522 153.689 150.489 68.5171 156.326  
  C++ Note: df101 -138.831 -138.831  
  C++ Note: df102 3.46414 0.365079  
  C++ Note: df103 -26.9449 -11.9287  
  C++ Note: df104 0.980196 0.504575  
  C++ Note: df105 -0.128564 -0.0306052  
  C++ Note: df106 -40.0765 -380.276  
  C++ Note: riskr checked 1069.02 1452.99 1849.81 1085.84 1647.1  
  C++ Note: riskl checked 115.522 153.689 150.489 68.5171 156.326  
  C++ Note: df101 -69.4154 -69.4154  
  C++ Note: df102 1.73207 0.18254  
  C++ Note: df103 -13.4724 -5.96434  
  C++ Note: df104 0.980196 0.504575  
  C++ Note: df105 -0.128564 -0.0306052  
  C++ Note: df106 -40.0765 -380.276  
  C++ Note: df501 -69.4154
  C++ Note: df504 0.9801959 0.5045754  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,64,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 771 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df102 20.2568 3.06352  
  C++ Note: df103 -19.2883 -6.30273  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -1.05021 -0.486062  
  C++ Note: df106 -4.03059 -26.6514  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.687658 0.264546  
  C++ Note: sums checked 5488.09 1160.81  
  C++ Note: risk checked 6335.61  
  C++ Note: risk1 checked 20721 3646.09  
  C++ Note: risk2 checked 82152.1 3646.09  
  C++ Note: riskr checked 377.766 488.297 734.919 474.772 620.092  
  C++ Note: riskl checked 33.7936 42.4291 53.0044 30.0313 47.37  
  C++ Note: df101 -70.7018 -70.7018  
  C++ Note: df102 5.88045 1.42637  
  C++ Note: df103 -16.141 -6.20425  
  C++ Note: df104 0.687658 0.264546  
  C++ Note: df105 -0.364317 -0.229902  
  C++ Note: df106 -12.0232 -49.5677  
  C++ Note: df100 19518 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 377.766 488.297 734.919 474.772 620.092  
  C++ Note: riskl checked 33.7936 42.4291 53.0044 30.0313 47.37  
  C++ Note: df101 -70.7018 -70.7018  
  C++ Note: df102 5.88045 1.42637  
  C++ Note: df103 -16.141 -6.20425  
  C++ Note: df104 0.687658 0.264546  
  C++ Note: df105 -0.364317 -0.229902  
  C++ Note: df106 -12.0232 -49.5677  
  C++ Note: ending guess 0
  C++ Note: df501 -70.70181
  C++ Note: df504 0.6876581 0.2645464  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.6876581 0.2645464, -70.70181<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.687658 0.264546  
  C++ Note: sums checked 5488.09 1160.81  
  C++ Note: risk checked 6335.61  
  C++ Note: risk1 checked 20721 3646.09  
  C++ Note: risk2 checked 82152.1 3646.09  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 377.766 488.297 734.919 474.772 620.092  
  C++ Note: riskl checked 33.7936 42.4291 53.0044 30.0313 47.37  
  C++ Note: df101 -70.7018 -70.7018  
  C++ Note: df102 5.88045 1.42637  
  C++ Note: df103 -16.141 -6.20425  
  C++ Note: df104 0.687658 0.264546  
  C++ Note: df105 -0.364317 -0.229902  
  C++ Note: df106 -12.0232 -49.5677  
  C++ Note: Starting Halves
  C++ Note: df501 -70.70181
  C++ Note: df504 0.6876581 0.2645464  
  C++ Note: values checked 0.960896 0.436973  
  C++ Note: sums checked 14572.6 1291  
  C++ Note: risk checked 18577.5  
  C++ Note: risk1 checked 71348.7 11312.9  
  C++ Note: risk2 checked 309667 11312.9  
  C++ Note: riskr checked 959.114 1296.18 1690.63 992.574 1493.38  
  C++ Note: riskl checked 101.047 135.091 136.789 61.9987 142.258  
  C++ Note: df101 -69.4764 -69.4764  
  C++ Note: df102 1.94332 0.57404  
  C++ Note: df103 -13.6394 -6.04201  
  C++ Note: df104 0.960896 0.436973  
  C++ Note: df105 -0.142478 -0.0950082  
  C++ Note: df106 -35.7515 -121.031  
  C++ Note: df100 28901 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 959.114 1296.18 1690.63 992.574 1493.38  
  C++ Note: riskl checked 101.047 135.091 136.789 61.9987 142.258  
  C++ Note: df101 -69.4764 -69.4764  
  C++ Note: df102 1.94332 0.57404  
  C++ Note: df103 -13.6394 -6.04201  
  C++ Note: df104 0.960896 0.436973  
  C++ Note: df105 -0.142478 -0.0950082  
  C++ Note: df106 -35.7515 -121.031  
  C++ Note: riskr checked 959.114 1296.18 1690.63 992.574 1493.38  
  C++ Note: riskl checked 101.047 135.091 136.789 61.9987 142.258  
  C++ Note: df101 -69.4764 -69.4764  
  C++ Note: df102 1.94332 0.57404  
  C++ Note: df103 -13.6394 -6.04201  
  C++ Note: df104 0.960896 0.436973  
  C++ Note: df105 -0.142478 -0.0950082  
  C++ Note: df106 -35.7515 -121.031  
  C++ Note: df501 -69.4764
  C++ Note: df504 0.9608958 0.4369729  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,77,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 802 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df102 4.95969 1.83647  
  C++ Note: df103 -8.02808 -6.24909  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -0.617793 -0.293878  
  C++ Note: df106 -15.8772 -42.8791  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.418727 0.23168  
  C++ Note: sums checked 2471.96 1138.44  
  C++ Note: risk checked 2806.83  
  C++ Note: risk1 checked 7403.07 1619.26  
  C++ Note: risk2 checked 26245.1 1619.26  
  C++ Note: riskr checked 204.962 228.222 404.667 376.889 329.957  
  C++ Note: riskl checked 13.6275 16.1481 23.6435 17.202 18.4589  
  C++ Note: df101 -76.7631 -76.7631  
  C++ Note: df102 1.20988 0.464091  
  C++ Note: df103 -8.05249 -6.08664  
  C++ Note: df104 0.418727 0.23168  
  C++ Note: df105 -0.15025 -0.0762476  
  C++ Note: df106 -63.4466 -165.405  
  C++ Note: df100 22599 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 204.962 228.222 404.667 376.889 329.957  
  C++ Note: riskl checked 13.6275 16.1481 23.6435 17.202 18.4589  
  C++ Note: df101 -76.7631 -76.7631  
  C++ Note: df102 1.20988 0.464091  
  C++ Note: df103 -8.05249 -6.08664  
  C++ Note: df104 0.418727 0.23168  
  C++ Note: df105 -0.15025 -0.0762476  
  C++ Note: df106 -63.4466 -165.405  
  C++ Note: ending guess 0
  C++ Note: df501 -76.76306
  C++ Note: df504 0.4187269 0.2316801  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.4187269 0.2316801, -76.76306<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.418727 0.23168  
  C++ Note: sums checked 2471.96 1138.44  
  C++ Note: risk checked 2806.83  
  C++ Note: risk1 checked 7403.07 1619.26  
  C++ Note: risk2 checked 26245.1 1619.26  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 204.962 228.222 404.667 376.889 329.957  
  C++ Note: riskl checked 13.6275 16.1481 23.6435 17.202 18.4589  
  C++ Note: df101 -76.7631 -76.7631  
  C++ Note: df102 1.20988 0.464091  
  C++ Note: df103 -8.05249 -6.08664  
  C++ Note: df104 0.418727 0.23168  
  C++ Note: df105 -0.15025 -0.0762476  
  C++ Note: df106 -63.4466 -165.405  
  C++ Note: Starting Halves
  C++ Note: df501 -76.76306
  C++ Note: df504 0.4187269 0.2316801  
  C++ Note: values checked 0.544462 0.314935  
  C++ Note: sums checked 3513.43 1196.56  
  C++ Note: risk checked 4183.37  
  C++ Note: risk1 checked 12279.1 2479.77  
  C++ Note: risk2 checked 45976.8 2479.77  
  C++ Note: riskr checked 310.384 340.338 594.633 508.23 483.864  
  C++ Note: riskl checked 22.1993 26.3463 35.4607 23.4318 28.9768  
  C++ Note: df101 -76.6438 -76.6438  
  C++ Note: df102 0.30343 0.116957  
  C++ Note: df103 -8.01098 -6.00926  
  C++ Note: df104 0.544462 0.314935  
  C++ Note: df105 -0.0378768 -0.0194628  
  C++ Note: df106 -252.591 -655.316  
  C++ Note: df100 31171 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 310.384 340.338 594.633 508.23 483.864  
  C++ Note: riskl checked 22.1993 26.3463 35.4607 23.4318 28.9768  
  C++ Note: df101 -76.6438 -76.6438  
  C++ Note: df102 0.30343 0.116957  
  C++ Note: df103 -8.01098 -6.00926  
  C++ Note: df104 0.544462 0.314935  
  C++ Note: df105 -0.0378768 -0.0194628  
  C++ Note: df106 -252.591 -655.316  
  C++ Note: riskr checked 310.384 340.338 594.633 508.23 483.864  
  C++ Note: riskl checked 22.1993 26.3463 35.4607 23.4318 28.9768  
  C++ Note: df101 -76.6438 -76.6438  
  C++ Note: df102 0.30343 0.116957  
  C++ Note: df103 -8.01098 -6.00926  
  C++ Note: df104 0.544462 0.314935  
  C++ Note: df105 -0.0378768 -0.0194628  
  C++ Note: df106 -252.591 -655.316  
  C++ Note: df501 -76.64377
  C++ Note: df504 0.5444616 0.3149349  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,80,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 747 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df102 4.95969 1.83647  
  C++ Note: df103 -8.02808 -6.24909  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -0.617793 -0.293878  
  C++ Note: df106 -15.8772 -42.8791  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.363345 0.120408  
  C++ Note: sums checked 2142.94 1067.95  
  C++ Note: risk checked 2285.92  
  C++ Note: risk1 checked 5735.21 1260.42  
  C++ Note: risk2 checked 19832 1260.42  
  C++ Note: riskr checked 164.565 184.907 330.338 318.961 267.68  
  C++ Note: riskl checked 10.2294 12.5089 19.0748 14.2341 14.809  
  C++ Note: df101 -76.9241 -76.9241  
  C++ Note: df102 1.51399 1.07663  
  C++ Note: df103 -8.05499 -6.1885  
  C++ Note: df104 0.363345 0.120408  
  C++ Note: df105 -0.187957 -0.173973  
  C++ Note: df106 -50.8089 -71.4489  
  C++ Note: df100 6275 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 164.565 184.907 330.338 318.961 267.68  
  C++ Note: riskl checked 10.2294 12.5089 19.0748 14.2341 14.809  
  C++ Note: df101 -153.848 -153.848  
  C++ Note: df102 3.02798 2.15326  
  C++ Note: df103 -16.11 -12.377  
  C++ Note: df104 0.363345 0.120408  
  C++ Note: df105 -0.187957 -0.173973  
  C++ Note: df106 -50.8089 -71.4489  
  C++ Note: ending guess 0
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.3633446 0.1204083, -153.8483<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df102 4.95969 1.83647  
  C++ Note: df103 -8.02808 -6.24909  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -0.617793 -0.293878  
  C++ Note: df106 -15.8772 -42.8791  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.363345 0.120408  
  C++ Note: sums checked 2142.94 1067.95  
  C++ Note: risk checked 2285.92  
  C++ Note: risk1 checked 5735.21 1260.42  
  C++ Note: risk2 checked 19832 1260.42  
  C++ Note: riskr checked 164.565 184.907 330.338 318.961 267.68  
  C++ Note: riskl checked 10.2294 12.5089 19.0748 14.2341 14.809  
  C++ Note: df101 -76.9241 -76.9241  
  C++ Note: df102 1.51399 1.07663  
  C++ Note: df103 -8.05499 -6.1885  
  C++ Note: df104 0.363345 0.120408  
  C++ Note: df105 -0.187957 -0.173973  
  C++ Note: df106 -50.8089 -71.4489  
  C++ Note: df100 40506 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 164.565 184.907 330.338 318.961 267.68  
  C++ Note: riskl checked 10.2294 12.5089 19.0748 14.2341 14.809  
  C++ Note: df101 -76.9241 -76.9241  
  C++ Note: df102 1.51399 1.07663  
  C++ Note: df103 -8.05499 -6.1885  
  C++ Note: df104 0.363345 0.120408  
  C++ Note: df105 -0.187957 -0.173973  
  C++ Note: df106 -50.8089 -71.4489  
  C++ Note: riskr checked 164.565 184.907 330.338 318.961 267.68  
  C++ Note: riskl checked 10.2294 12.5089 19.0748 14.2341 14.809  
  C++ Note: df101 -76.9241 -76.9241  
  C++ Note: df102 1.51399 1.07663  
  C++ Note: df103 -8.05499 -6.1885  
  C++ Note: df104 0.363345 0.120408  
  C++ Note: df105 -0.187957 -0.173973  
  C++ Note: df106 -50.8089 -71.4489  
  C++ Note: df501 -76.92413
  C++ Note: df504 0.3633446 0.1204083  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,88,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 843 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 13923 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 15299 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -81.64684<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 19107 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 31304 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,77,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 14894 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 17973 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -163.294 -163.294  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 34995 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -81.64684<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 38981 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 40300 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,63,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 14837 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 22263 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 23559 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -78.74604<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 27093 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 28333 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,67,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 756 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 3425 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 4688 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -78.74604<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 8233 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 9490 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,73,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 830 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: derivs checked 1229.85 410.233  
  C++ Note: second derivs checked 3319.14 410.233  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df102 20.2568 3.06352  
  C++ Note: df103 -19.2883 -6.30273  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -1.05021 -0.486062  
  C++ Note: df106 -4.03059 -26.6514  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.71116 0.38487  
  C++ Note: sums checked 7349.12 7349.12  
  C++ Note: derivs checked 24395.8 4437.37  
  C++ Note: second derivs checked 97505.9 4437.37  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 7349.12  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 7349.12  
  C++ Note: risk checked 7349.12  
  C++ Note: risk1 checked 24395.8 4437.37  
  C++ Note: risk2 checked 97505.9 4437.37  
  C++ Note: riskr checked 435.702 565.97 827.445 534.224 709.522  
  C++ Note: riskl checked 41.2127 50.5438 60.5747 34.7714 53.678  
  C++ Note: df101 -70.439 -70.439  
  C++ Note: df102 5.59432 0.70352  
  C++ Note: df103 -15.9304 -6.09947  
  C++ Note: df104 0.71116 0.38487  
  C++ Note: df105 -0.351173 -0.115341  
  C++ Note: df106 -12.5912 -100.124  
  C++ Note: df100 11302 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 435.702 565.97 827.445 534.224 709.522  
  C++ Note: riskl checked 41.2127 50.5438 60.5747 34.7714 53.678  
  C++ Note: df101 -70.439 -70.439  
  C++ Note: df102 5.59432 0.70352  
  C++ Note: df103 -15.9304 -6.09947  
  C++ Note: df104 0.71116 0.38487  
  C++ Note: df105 -0.351173 -0.115341  
  C++ Note: df106 -12.5912 -100.124  
  C++ Note: ending guess 0
  C++ Note: df501 -70.43896
  C++ Note: df504 0.7111601 0.3848703  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.7111601 0.3848703, -70.43896<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.71116 0.38487  
  C++ Note: sums checked 7349.12 7349.12  
  C++ Note: derivs checked 24395.8 4437.37  
  C++ Note: second derivs checked 97505.9 4437.37  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 7349.12  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 7349.12  
  C++ Note: risk checked 7349.12  
  C++ Note: risk1 checked 24395.8 4437.37  
  C++ Note: risk2 checked 97505.9 4437.37  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 435.702 565.97 827.445 534.224 709.522  
  C++ Note: riskl checked 41.2127 50.5438 60.5747 34.7714 53.678  
  C++ Note: df101 -70.439 -70.439  
  C++ Note: df102 5.59432 0.70352  
  C++ Note: df103 -15.9304 -6.09947  
  C++ Note: df104 0.71116 0.38487  
  C++ Note: df105 -0.351173 -0.115341  
  C++ Note: df106 -12.5912 -100.124  
  C++ Note: Starting Halves
  C++ Note: df501 -70.43896
  C++ Note: df504 0.7111601 0.3848703  
  C++ Note: values checked 0.980196 0.504575  
  C++ Note: sums checked 20865.8 20865.8  
  C++ Note: derivs checked 80872.8 13030.7  
  C++ Note: second derivs checked 352964 13030.7  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 20865.8  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 20865.8  
  C++ Note: risk checked 20865.8  
  C++ Note: risk1 checked 80872.8 13030.7  
  C++ Note: risk2 checked 352964 13030.7  
  C++ Note: riskr checked 1069.02 1452.99 1849.81 1085.84 1647.1  
  C++ Note: riskl checked 115.522 153.689 150.489 68.5171 156.326  
  C++ Note: df101 -69.4154 -69.4154  
  C++ Note: df102 1.73207 0.18254  
  C++ Note: df103 -13.4724 -5.96434  
  C++ Note: df104 0.980196 0.504575  
  C++ Note: df105 -0.128564 -0.0306052  
  C++ Note: df106 -40.0765 -380.276  
  C++ Note: df100 20930 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 1069.02 1452.99 1849.81 1085.84 1647.1  
  C++ Note: riskl checked 115.522 153.689 150.489 68.5171 156.326  
  C++ Note: df101 -69.4154 -69.4154  
  C++ Note: df102 1.73207 0.18254  
  C++ Note: df103 -13.4724 -5.96434  
  C++ Note: df104 0.980196 0.504575  
  C++ Note: df105 -0.128564 -0.0306052  
  C++ Note: df106 -40.0765 -380.276  
  C++ Note: riskr checked 1069.02 1452.99 1849.81 1085.84 1647.1  
  C++ Note: riskl checked 115.522 153.689 150.489 68.5171 156.326  
  C++ Note: df101 -69.4154 -69.4154  
  C++ Note: df102 1.73207 0.18254  
  C++ Note: df103 -13.4724 -5.96434  
  C++ Note: df104 0.980196 0.504575  
  C++ Note: df105 -0.128564 -0.0306052  
  C++ Note: df106 -40.0765 -380.276  
  C++ Note: df501 -69.4154
  C++ Note: df504 0.9801959 0.5045754  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,74,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 868 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: derivs checked 1229.85 410.233  
  C++ Note: second derivs checked 3319.14 410.233  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 54.6632 67.7751 134.33 104.897 91.076  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -81.6468 -81.6468  
  C++ Note: df102 20.2568 3.06352  
  C++ Note: df103 -19.2883 -6.30273  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -1.05021 -0.486062  
  C++ Note: df106 -4.03059 -26.6514  
  C++ Note: Starting Halves
  C++ Note: df501 -81.64684
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.687658 0.264546  
  C++ Note: sums checked 6335.61 6335.61  
  C++ Note: derivs checked 20721 3646.09  
  C++ Note: second derivs checked 82152.1 3646.09  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 6335.61  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 6335.61  
  C++ Note: risk checked 6335.61  
  C++ Note: risk1 checked 20721 3646.09  
  C++ Note: risk2 checked 82152.1 3646.09  
  C++ Note: riskr checked 377.766 488.297 734.919 474.772 620.092  
  C++ Note: riskl checked 33.7936 42.4291 53.0044 30.0313 47.37  
  C++ Note: df101 -70.7018 -70.7018  
  C++ Note: df102 5.88045 1.42637  
  C++ Note: df103 -16.141 -6.20425  
  C++ Note: df104 0.687658 0.264546  
  C++ Note: df105 -0.364317 -0.229902  
  C++ Note: df106 -12.0232 -49.5677  
  C++ Note: df100 24018 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 377.766 488.297 734.919 474.772 620.092  
  C++ Note: riskl checked 33.7936 42.4291 53.0044 30.0313 47.37  
  C++ Note: df101 -70.7018 -70.7018  
  C++ Note: df102 5.88045 1.42637  
  C++ Note: df103 -16.141 -6.20425  
  C++ Note: df104 0.687658 0.264546  
  C++ Note: df105 -0.364317 -0.229902  
  C++ Note: df106 -12.0232 -49.5677  
  C++ Note: ending guess 0
  C++ Note: df501 -70.70181
  C++ Note: df504 0.6876581 0.2645464  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.6876581 0.2645464, -70.70181<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.687658 0.264546  
  C++ Note: sums checked 6335.61 6335.61  
  C++ Note: derivs checked 20721 3646.09  
  C++ Note: second derivs checked 82152.1 3646.09  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 6335.61  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 6335.61  
  C++ Note: risk checked 6335.61  
  C++ Note: risk1 checked 20721 3646.09  
  C++ Note: risk2 checked 82152.1 3646.09  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 377.766 488.297 734.919 474.772 620.092  
  C++ Note: riskl checked 33.7936 42.4291 53.0044 30.0313 47.37  
  C++ Note: df101 -70.7018 -70.7018  
  C++ Note: df102 5.88045 1.42637  
  C++ Note: df103 -16.141 -6.20425  
  C++ Note: df104 0.687658 0.264546  
  C++ Note: df105 -0.364317 -0.229902  
  C++ Note: df106 -12.0232 -49.5677  
  C++ Note: Starting Halves
  C++ Note: df501 -70.70181
  C++ Note: df504 0.6876581 0.2645464  
  C++ Note: values checked 0.960896 0.436973  
  C++ Note: sums checked 18577.5 18577.5  
  C++ Note: derivs checked 71348.7 11312.9  
  C++ Note: second derivs checked 309667 11312.9  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 18577.5  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 18577.5  
  C++ Note: risk checked 18577.5  
  C++ Note: risk1 checked 71348.7 11312.9  
  C++ Note: risk2 checked 309667 11312.9  
  C++ Note: riskr checked 959.114 1296.18 1690.63 992.574 1493.38  
  C++ Note: riskl checked 101.047 135.091 136.789 61.9987 142.258  
  C++ Note: df101 -69.4764 -69.4764  
  C++ Note: df102 1.94332 0.57404  
  C++ Note: df103 -13.6394 -6.04201  
  C++ Note: df104 0.960896 0.436973  
  C++ Note: df105 -0.142478 -0.0950082  
  C++ Note: df106 -35.7515 -121.031  
  C++ Note: df100 33953 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:30 2023
  
  C++ Note: riskr checked 959.114 1296.18 1690.63 992.574 1493.38  
  C++ Note: riskl checked 101.047 135.091 136.789 61.9987 142.258  
  C++ Note: df101 -69.4764 -69.4764  
  C++ Note: df102 1.94332 0.57404  
  C++ Note: df103 -13.6394 -6.04201  
  C++ Note: df104 0.960896 0.436973  
  C++ Note: df105 -0.142478 -0.0950082  
  C++ Note: df106 -35.7515 -121.031  
  C++ Note: riskr checked 959.114 1296.18 1690.63 992.574 1493.38  
  C++ Note: riskl checked 101.047 135.091 136.789 61.9987 142.258  
  C++ Note: df101 -69.4764 -69.4764  
  C++ Note: df102 1.94332 0.57404  
  C++ Note: df103 -13.6394 -6.04201  
  C++ Note: df104 0.960896 0.436973  
  C++ Note: df105 -0.142478 -0.0950082  
  C++ Note: df106 -35.7515 -121.031  
  C++ Note: df501 -69.4764
  C++ Note: df504 0.9608958 0.4369729  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,65,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 749 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: derivs checked 1229.85 410.233  
  C++ Note: second derivs checked 3319.14 410.233  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df102 4.95969 1.83647  
  C++ Note: df103 -8.02808 -6.24909  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -0.617793 -0.293878  
  C++ Note: df106 -15.8772 -42.8791  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.418727 0.23168  
  C++ Note: sums checked 2806.83 2806.83  
  C++ Note: derivs checked 7403.07 1619.26  
  C++ Note: second derivs checked 26245.1 1619.26  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 2806.83  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 2806.83  
  C++ Note: risk checked 2806.83  
  C++ Note: risk1 checked 7403.07 1619.26  
  C++ Note: risk2 checked 26245.1 1619.26  
  C++ Note: riskr checked 204.962 228.222 404.667 376.889 329.957  
  C++ Note: riskl checked 13.6275 16.1481 23.6435 17.202 18.4589  
  C++ Note: df101 -76.7631 -76.7631  
  C++ Note: df102 1.20988 0.464091  
  C++ Note: df103 -8.05249 -6.08664  
  C++ Note: df104 0.418727 0.23168  
  C++ Note: df105 -0.15025 -0.0762476  
  C++ Note: df106 -63.4466 -165.405  
  C++ Note: df100 6985 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 204.962 228.222 404.667 376.889 329.957  
  C++ Note: riskl checked 13.6275 16.1481 23.6435 17.202 18.4589  
  C++ Note: df101 -76.7631 -76.7631  
  C++ Note: df102 1.20988 0.464091  
  C++ Note: df103 -8.05249 -6.08664  
  C++ Note: df104 0.418727 0.23168  
  C++ Note: df105 -0.15025 -0.0762476  
  C++ Note: df106 -63.4466 -165.405  
  C++ Note: ending guess 0
  C++ Note: df501 -76.76306
  C++ Note: df504 0.4187269 0.2316801  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.4187269 0.2316801, -76.76306<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.418727 0.23168  
  C++ Note: sums checked 2806.83 2806.83  
  C++ Note: derivs checked 7403.07 1619.26  
  C++ Note: second derivs checked 26245.1 1619.26  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 2806.83  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 2806.83  
  C++ Note: risk checked 2806.83  
  C++ Note: risk1 checked 7403.07 1619.26  
  C++ Note: risk2 checked 26245.1 1619.26  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 204.962 228.222 404.667 376.889 329.957  
  C++ Note: riskl checked 13.6275 16.1481 23.6435 17.202 18.4589  
  C++ Note: df101 -76.7631 -76.7631  
  C++ Note: df102 1.20988 0.464091  
  C++ Note: df103 -8.05249 -6.08664  
  C++ Note: df104 0.418727 0.23168  
  C++ Note: df105 -0.15025 -0.0762476  
  C++ Note: df106 -63.4466 -165.405  
  C++ Note: Starting Halves
  C++ Note: df501 -76.76306
  C++ Note: df504 0.4187269 0.2316801  
  C++ Note: values checked 0.544462 0.314935  
  C++ Note: sums checked 4183.37 4183.37  
  C++ Note: derivs checked 12279.1 2479.77  
  C++ Note: second derivs checked 45976.8 2479.77  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 4183.37  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 4183.37  
  C++ Note: risk checked 4183.37  
  C++ Note: risk1 checked 12279.1 2479.77  
  C++ Note: risk2 checked 45976.8 2479.77  
  C++ Note: riskr checked 310.384 340.338 594.633 508.23 483.864  
  C++ Note: riskl checked 22.1993 26.3463 35.4607 23.4318 28.9768  
  C++ Note: df101 -76.6438 -76.6438  
  C++ Note: df102 0.30343 0.116957  
  C++ Note: df103 -8.01098 -6.00926  
  C++ Note: df104 0.544462 0.314935  
  C++ Note: df105 -0.0378768 -0.0194628  
  C++ Note: df106 -252.591 -655.316  
  C++ Note: df100 24732 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 310.384 340.338 594.633 508.23 483.864  
  C++ Note: riskl checked 22.1993 26.3463 35.4607 23.4318 28.9768  
  C++ Note: df101 -76.6438 -76.6438  
  C++ Note: df102 0.30343 0.116957  
  C++ Note: df103 -8.01098 -6.00926  
  C++ Note: df104 0.544462 0.314935  
  C++ Note: df105 -0.0378768 -0.0194628  
  C++ Note: df106 -252.591 -655.316  
  C++ Note: riskr checked 310.384 340.338 594.633 508.23 483.864  
  C++ Note: riskl checked 22.1993 26.3463 35.4607 23.4318 28.9768  
  C++ Note: df101 -76.6438 -76.6438  
  C++ Note: df102 0.30343 0.116957  
  C++ Note: df103 -8.01098 -6.00926  
  C++ Note: df104 0.544462 0.314935  
  C++ Note: df105 -0.0378768 -0.0194628  
  C++ Note: df106 -252.591 -655.316  
  C++ Note: df501 -76.64377
  C++ Note: df504 0.5444616 0.3149349  
  Note: 5  strata used
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,93,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 1938 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: derivs checked 1229.85 410.233  
  C++ Note: second derivs checked 3319.14 410.233  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 48.2797 60.3592 110.435 136.268 86.2042  
  C++ Note: riskl checked 2.03195 2.97617 5.24121 5.60277 3.75773  
  C++ Note: df101 -78.746 -78.746  
  C++ Note: df102 4.95969 1.83647  
  C++ Note: df103 -8.02808 -6.24909  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -0.617793 -0.293878  
  C++ Note: df106 -15.8772 -42.8791  
  C++ Note: Starting Halves
  C++ Note: df501 -78.74604
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.363345 0.120408  
  C++ Note: sums checked 2285.92 2285.92  
  C++ Note: derivs checked 5735.21 1260.42  
  C++ Note: second derivs checked 19832 1260.42  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 2285.92  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 2285.92  
  C++ Note: risk checked 2285.92  
  C++ Note: risk1 checked 5735.21 1260.42  
  C++ Note: risk2 checked 19832 1260.42  
  C++ Note: riskr checked 164.565 184.907 330.338 318.961 267.68  
  C++ Note: riskl checked 10.2294 12.5089 19.0748 14.2341 14.809  
  C++ Note: df101 -76.9241 -76.9241  
  C++ Note: df102 1.51399 1.07663  
  C++ Note: df103 -8.05499 -6.1885  
  C++ Note: df104 0.363345 0.120408  
  C++ Note: df105 -0.187957 -0.173973  
  C++ Note: df106 -50.8089 -71.4489  
  C++ Note: df100 8646 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 164.565 184.907 330.338 318.961 267.68  
  C++ Note: riskl checked 10.2294 12.5089 19.0748 14.2341 14.809  
  C++ Note: df101 -76.9241 -76.9241  
  C++ Note: df102 1.51399 1.07663  
  C++ Note: df103 -8.05499 -6.1885  
  C++ Note: df104 0.363345 0.120408  
  C++ Note: df105 -0.187957 -0.173973  
  C++ Note: df106 -50.8089 -71.4489  
  C++ Note: ending guess 0
  C++ Note: df501 -76.92413
  C++ Note: df504 0.3633446 0.1204083  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.3633446 0.1204083, -76.92413<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.363345 0.120408  
  C++ Note: sums checked 2285.92 2285.92  
  C++ Note: derivs checked 5735.21 1260.42  
  C++ Note: second derivs checked 19832 1260.42  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 2285.92  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 2285.92  
  C++ Note: risk checked 2285.92  
  C++ Note: risk1 checked 5735.21 1260.42  
  C++ Note: risk2 checked 19832 1260.42  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 164.565 184.907 330.338 318.961 267.68  
  C++ Note: riskl checked 10.2294 12.5089 19.0748 14.2341 14.809  
  C++ Note: df101 -76.9241 -76.9241  
  C++ Note: df102 1.51399 1.07663  
  C++ Note: df103 -8.05499 -6.1885  
  C++ Note: df104 0.363345 0.120408  
  C++ Note: df105 -0.187957 -0.173973  
  C++ Note: df106 -50.8089 -71.4489  
  C++ Note: Starting Halves
  C++ Note: df501 -76.92413
  C++ Note: df504 0.3633446 0.1204083  
  C++ Note: values checked 0.504312 0.250888  
  C++ Note: sums checked 3588.12 3588.12  
  C++ Note: derivs checked 10196.7 2076.23  
  C++ Note: second derivs checked 37550.1 2076.23  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 3588.12  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 3588.12  
  C++ Note: risk checked 3588.12  
  C++ Note: risk1 checked 10196.7 2076.23  
  C++ Note: risk2 checked 37550.1 2076.23  
  C++ Note: riskr checked 264.882 291.296 513.751 450.881 417.012  
  C++ Note: riskl checked 18.2813 21.8994 30.4855 20.5786 24.6812  
  C++ Note: df101 -76.6791 -76.6791  
  C++ Note: df102 0.546122 0.454524  
  C++ Note: df103 -8.01926 -6.07942  
  C++ Note: df104 0.504312 0.250888  
  C++ Note: df105 -0.0681013 -0.0747644  
  C++ Note: df106 -140.407 -168.702  
  C++ Note: df100 19652 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 264.882 291.296 513.751 450.881 417.012  
  C++ Note: riskl checked 18.2813 21.8994 30.4855 20.5786 24.6812  
  C++ Note: df101 -76.6791 -76.6791  
  C++ Note: df102 0.546122 0.454524  
  C++ Note: df103 -8.01926 -6.07942  
  C++ Note: df104 0.504312 0.250888  
  C++ Note: df105 -0.0681013 -0.0747644  
  C++ Note: df106 -140.407 -168.702  
  C++ Note: riskr checked 264.882 291.296 513.751 450.881 417.012  
  C++ Note: riskl checked 18.2813 21.8994 30.4855 20.5786 24.6812  
  C++ Note: df101 -76.6791 -76.6791  
  C++ Note: df102 0.546122 0.454524  
  C++ Note: df103 -8.01926 -6.07942  
  C++ Note: df104 0.504312 0.250888  
  C++ Note: df105 -0.0681013 -0.0747644  
  C++ Note: df106 -140.407 -168.702  
  C++ Note: df501 -76.67911
  C++ Note: df504 0.504312 0.250888  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,75,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 501 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 2205 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 3035 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -122.8909<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 5208 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 5975 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,78,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 522 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 2234 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 3066 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -122.8909<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 5311 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 6145 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,60,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 374 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 1660 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 2274 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -119.9814<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 3898 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 4488 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,72,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 391 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 1664 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 2275 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -239.963 -239.963  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -239.9629<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 5581 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 6187 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,80,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 499 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: risk1r checked 3174.27 1089.12  
  C++ Note: risk2r checked 7204.63 1089.12  
  C++ Note: riskl checked 19.6098  
  C++ Note: risk1l checked 42.0717 11.5472  
  C++ Note: risk2l checked 118.124 11.5472  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df102 21.2331 3.11507  
  C++ Note: df103 -19.7104 -6.49727  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -1.07726 -0.479443  
  C++ Note: df106 -5.78769 -39.4505  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.732916 0.388699  
  C++ Note: sums checked 6380.99 1252.26  
  C++ Note: risk checked 7921.99  
  C++ Note: risk1 checked 26681.9 4784.79  
  C++ Note: risk2 checked 107491 4784.79  
  C++ Note: riskr checked 15672.9  
  C++ Note: risk1r checked 42701.5 9198.27  
  C++ Note: risk2r checked 144140 9198.27  
  C++ Note: riskl checked 259.026  
  C++ Note: risk1l checked 843.134 168.735  
  C++ Note: risk2l checked 3047.41 168.735  
  C++ Note: df101 -110.801 -110.801  
  C++ Note: df102 6.10212 0.649377  
  C++ Note: df103 -15.9738 -6.28124  
  C++ Note: df104 0.732916 0.388699  
  C++ Note: df105 -0.382009 -0.103384  
  C++ Note: df106 -18.1578 -170.627  
  C++ Note: df100 14164 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 15672.9  
  C++ Note: risk1r checked 42701.5 9198.27  
  C++ Note: risk2r checked 144140 9198.27  
  C++ Note: riskl checked 259.026  
  C++ Note: risk1l checked 843.134 168.735  
  C++ Note: risk2l checked 3047.41 168.735  
  C++ Note: df101 -110.801 -110.801  
  C++ Note: df102 6.10212 0.649377  
  C++ Note: df103 -15.9738 -6.28124  
  C++ Note: df104 0.732916 0.388699  
  C++ Note: df105 -0.382009 -0.103384  
  C++ Note: df106 -18.1578 -170.627  
  C++ Note: ending guess 0
  C++ Note: df501 -110.8014
  C++ Note: df504 0.732916 0.3886995  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.732916 0.3886995, -110.8014<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.732916 0.388699  
  C++ Note: sums checked 6380.99 1252.26  
  C++ Note: risk checked 7921.99  
  C++ Note: risk1 checked 26681.9 4784.79  
  C++ Note: risk2 checked 107491 4784.79  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 15672.9  
  C++ Note: risk1r checked 42701.5 9198.27  
  C++ Note: risk2r checked 144140 9198.27  
  C++ Note: riskl checked 259.026  
  C++ Note: risk1l checked 843.134 168.735  
  C++ Note: risk2l checked 3047.41 168.735  
  C++ Note: df101 -110.801 -110.801  
  C++ Note: df102 6.10212 0.649377  
  C++ Note: df103 -15.9738 -6.28124  
  C++ Note: df104 0.732916 0.388699  
  C++ Note: df105 -0.382009 -0.103384  
  C++ Note: df106 -18.1578 -170.627  
  C++ Note: Starting Halves
  C++ Note: df501 -110.8014
  C++ Note: df504 0.732916 0.3886995  
  C++ Note: values checked 1.02333 0.493704  
  C++ Note: sums checked 18600.8 1338.98  
  C++ Note: risk checked 24538.9  
  C++ Note: risk1 checked 97084.4 15240.1  
  C++ Note: risk2 checked 428953 15240.1  
  C++ Note: riskr checked 39636.5  
  C++ Note: risk1r checked 128036 24066.7  
  C++ Note: risk2r checked 480878 24066.7  
  C++ Note: riskl checked 745.302  
  C++ Note: risk1l checked 2645.43 469.387  
  C++ Note: risk2l checked 10112.8 469.387  
  C++ Note: df101 -109.621 -109.621  
  C++ Note: df102 1.83938 0.14137  
  C++ Note: df103 -13.8104 -6.17729  
  C++ Note: df104 1.02333 0.493704  
  C++ Note: df105 -0.133188 -0.0228854  
  C++ Note: df106 -59.5969 -775.422  
  C++ Note: df100 21115 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 39636.5  
  C++ Note: risk1r checked 128036 24066.7  
  C++ Note: risk2r checked 480878 24066.7  
  C++ Note: riskl checked 745.302  
  C++ Note: risk1l checked 2645.43 469.387  
  C++ Note: risk2l checked 10112.8 469.387  
  C++ Note: df101 -109.621 -109.621  
  C++ Note: df102 1.83938 0.14137  
  C++ Note: df103 -13.8104 -6.17729  
  C++ Note: df104 1.02333 0.493704  
  C++ Note: df105 -0.133188 -0.0228854  
  C++ Note: df106 -59.5969 -775.422  
  C++ Note: riskr checked 39636.5  
  C++ Note: risk1r checked 128036 24066.7  
  C++ Note: risk2r checked 480878 24066.7  
  C++ Note: riskl checked 745.302  
  C++ Note: risk1l checked 2645.43 469.387  
  C++ Note: risk2l checked 10112.8 469.387  
  C++ Note: df101 -109.621 -109.621  
  C++ Note: df102 1.83938 0.14137  
  C++ Note: df103 -13.8104 -6.17729  
  C++ Note: df104 1.02333 0.493704  
  C++ Note: df105 -0.133188 -0.0228854  
  C++ Note: df106 -59.5969 -775.422  
  C++ Note: df501 -109.6211
  C++ Note: df504 1.023328 0.4937042  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,64,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 475 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: risk1r checked 3174.27 1089.12  
  C++ Note: risk2r checked 7204.63 1089.12  
  C++ Note: riskl checked 19.6098  
  C++ Note: risk1l checked 42.0717 11.5472  
  C++ Note: risk2l checked 118.124 11.5472  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df102 21.2331 3.11507  
  C++ Note: df103 -19.7104 -6.49727  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -1.07726 -0.479443  
  C++ Note: df106 -5.78769 -39.4505  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.707943 0.259582  
  C++ Note: sums checked 5868.37 1157.38  
  C++ Note: risk checked 6754.07  
  C++ Note: risk1 checked 22400.3 3873.99  
  C++ Note: risk2 checked 89482.9 3873.99  
  C++ Note: riskr checked 13607.5  
  C++ Note: risk1r checked 36518.1 7564.8  
  C++ Note: risk2r checked 122057 7564.8  
  C++ Note: riskl checked 219.94  
  C++ Note: risk1l checked 713.45 137.505  
  C++ Note: risk2l checked 2579.26 137.505  
  C++ Note: df101 -111.093 -111.093  
  C++ Note: df102 6.4244 1.45354  
  C++ Note: df103 -16.1091 -6.40177  
  C++ Note: df104 0.707943 0.259582  
  C++ Note: df105 -0.398805 -0.227053  
  C++ Note: df106 -17.2924 -76.4296  
  C++ Note: df100 5367 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 13607.5  
  C++ Note: risk1r checked 36518.1 7564.8  
  C++ Note: risk2r checked 122057 7564.8  
  C++ Note: riskl checked 219.94  
  C++ Note: risk1l checked 713.45 137.505  
  C++ Note: risk2l checked 2579.26 137.505  
  C++ Note: df101 -111.093 -111.093  
  C++ Note: df102 6.4244 1.45354  
  C++ Note: df103 -16.1091 -6.40177  
  C++ Note: df104 0.707943 0.259582  
  C++ Note: df105 -0.398805 -0.227053  
  C++ Note: df106 -17.2924 -76.4296  
  C++ Note: ending guess 0
  C++ Note: df501 -111.0934
  C++ Note: df504 0.7079435 0.259582  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.7079435 0.259582, -111.0934<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.707943 0.259582  
  C++ Note: sums checked 5868.37 1157.38  
  C++ Note: risk checked 6754.07  
  C++ Note: risk1 checked 22400.3 3873.99  
  C++ Note: risk2 checked 89482.9 3873.99  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 13607.5  
  C++ Note: risk1r checked 36518.1 7564.8  
  C++ Note: risk2r checked 122057 7564.8  
  C++ Note: riskl checked 219.94  
  C++ Note: risk1l checked 713.45 137.505  
  C++ Note: risk2l checked 2579.26 137.505  
  C++ Note: df101 -111.093 -111.093  
  C++ Note: df102 6.4244 1.45354  
  C++ Note: df103 -16.1091 -6.40177  
  C++ Note: df104 0.707943 0.259582  
  C++ Note: df105 -0.398805 -0.227053  
  C++ Note: df106 -17.2924 -76.4296  
  C++ Note: Starting Halves
  C++ Note: df501 -111.0934
  C++ Note: df504 0.7079435 0.259582  
  C++ Note: values checked 1.00705 0.429872  
  C++ Note: sums checked 17441.8 1285.18  
  C++ Note: risk checked 22129.4  
  C++ Note: risk1 checked 86917.6 13416  
  C++ Note: risk2 checked 382294 13416  
  C++ Note: riskr checked 36201.7  
  C++ Note: risk1r checked 115958 21431.5  
  C++ Note: risk2r checked 433026 21431.5  
  C++ Note: riskl checked 676.025  
  C++ Note: risk1l checked 2396.11 417.501  
  C++ Note: risk2l checked 9159.18 417.501  
  C++ Note: df101 -109.674 -109.674  
  C++ Note: df102 2.03825 0.531514  
  C++ Note: df103 -13.8822 -6.25712  
  C++ Note: df104 1.00705 0.429872  
  C++ Note: df105 -0.146825 -0.0849455  
  C++ Note: df106 -53.8081 -206.343  
  C++ Note: df100 20867 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 36201.7  
  C++ Note: risk1r checked 115958 21431.5  
  C++ Note: risk2r checked 433026 21431.5  
  C++ Note: riskl checked 676.025  
  C++ Note: risk1l checked 2396.11 417.501  
  C++ Note: risk2l checked 9159.18 417.501  
  C++ Note: df101 -109.674 -109.674  
  C++ Note: df102 2.03825 0.531514  
  C++ Note: df103 -13.8822 -6.25712  
  C++ Note: df104 1.00705 0.429872  
  C++ Note: df105 -0.146825 -0.0849455  
  C++ Note: df106 -53.8081 -206.343  
  C++ Note: riskr checked 36201.7  
  C++ Note: risk1r checked 115958 21431.5  
  C++ Note: risk2r checked 433026 21431.5  
  C++ Note: riskl checked 676.025  
  C++ Note: risk1l checked 2396.11 417.501  
  C++ Note: risk2l checked 9159.18 417.501  
  C++ Note: df101 -109.674 -109.674  
  C++ Note: df102 2.03825 0.531514  
  C++ Note: df103 -13.8822 -6.25712  
  C++ Note: df104 1.00705 0.429872  
  C++ Note: df105 -0.146825 -0.0849455  
  C++ Note: df106 -53.8081 -206.343  
  C++ Note: df501 -109.6742
  C++ Note: df504 1.007047 0.4298716  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,65,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 468 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: risk1r checked 3418.73 1095.31  
  C++ Note: risk2r checked 8667.81 1095.31  
  C++ Note: riskl checked 19.6098  
  C++ Note: risk1l checked 42.0717 11.5472  
  C++ Note: risk2l checked 118.124 11.5472  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df102 6.06579 2.41134  
  C++ Note: df103 -8.60689 -6.47374  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -0.70476 -0.37248  
  C++ Note: df106 -19.78 -49.7572  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.497478 0.312164  
  C++ Note: sums checked 3067.26 1194.55  
  C++ Note: risk checked 3648.05  
  C++ Note: risk1 checked 10299.6 2165.99  
  C++ Note: risk2 checked 37798.4 2165.99  
  C++ Note: riskr checked 9367.5  
  C++ Note: risk1r checked 24562.6 5580.77  
  C++ Note: risk2r checked 81557.6 5580.77  
  C++ Note: riskl checked 118.249  
  C++ Note: risk1l checked 351.472 78.443  
  C++ Note: risk2l checked 1199.14 78.443  
  C++ Note: df101 -117.142 -117.142  
  C++ Note: df102 1.31609 0.547704  
  C++ Note: df103 -9.05233 -6.2666  
  C++ Note: df104 0.497478 0.312164  
  C++ Note: df105 -0.145387 -0.0874005  
  C++ Note: df106 -89.0079 -213.879  
  C++ Note: df100 2891 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 9367.5  
  C++ Note: risk1r checked 24562.6 5580.77  
  C++ Note: risk2r checked 81557.6 5580.77  
  C++ Note: riskl checked 118.249  
  C++ Note: risk1l checked 351.472 78.443  
  C++ Note: risk2l checked 1199.14 78.443  
  C++ Note: df101 -117.142 -117.142  
  C++ Note: df102 1.31609 0.547704  
  C++ Note: df103 -9.05233 -6.2666  
  C++ Note: df104 0.497478 0.312164  
  C++ Note: df105 -0.145387 -0.0874005  
  C++ Note: df106 -89.0079 -213.879  
  C++ Note: ending guess 0
  C++ Note: df501 -117.1424
  C++ Note: df504 0.4974778 0.3121644  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.4974778 0.3121644, -117.1424<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.497478 0.312164  
  C++ Note: sums checked 3067.26 1194.55  
  C++ Note: risk checked 3648.05  
  C++ Note: risk1 checked 10299.6 2165.99  
  C++ Note: risk2 checked 37798.4 2165.99  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 9367.5  
  C++ Note: risk1r checked 24562.6 5580.77  
  C++ Note: risk2r checked 81557.6 5580.77  
  C++ Note: riskl checked 118.249  
  C++ Note: risk1l checked 351.472 78.443  
  C++ Note: risk2l checked 1199.14 78.443  
  C++ Note: df101 -117.142 -117.142  
  C++ Note: df102 1.31609 0.547704  
  C++ Note: df103 -9.05233 -6.2666  
  C++ Note: df104 0.497478 0.312164  
  C++ Note: df105 -0.145387 -0.0874005  
  C++ Note: df106 -89.0079 -213.879  
  C++ Note: Starting Halves
  C++ Note: df501 -117.1424
  C++ Note: df504 0.4974778 0.3121644  
  C++ Note: values checked 0.617144 0.398893  
  C++ Note: sums checked 4379.75 1260.28  
  C++ Note: risk checked 5479.95  
  C++ Note: risk1 checked 17006.9 3344.7  
  C++ Note: risk2 checked 65563.9 3344.7  
  C++ Note: riskr checked 13683.9  
  C++ Note: risk1r checked 38812.2 8366.11  
  C++ Note: risk2r checked 134810 8366.11  
  C++ Note: riskl checked 180.348  
  C++ Note: risk1l checked 561.69 120.669  
  C++ Note: risk2l checked 1971.73 120.669  
  C++ Note: df101 -117.015 -117.015  
  C++ Note: df102 0.320802 0.13496  
  C++ Note: df103 -9.12088 -6.18217  
  C++ Note: df104 0.617144 0.398893  
  C++ Note: df105 -0.0351723 -0.0218306  
  C++ Note: df106 -364.756 -867.031  
  C++ Note: df100 6377 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 13683.9  
  C++ Note: risk1r checked 38812.2 8366.11  
  C++ Note: risk2r checked 134810 8366.11  
  C++ Note: riskl checked 180.348  
  C++ Note: risk1l checked 561.69 120.669  
  C++ Note: risk2l checked 1971.73 120.669  
  C++ Note: df101 -117.015 -117.015  
  C++ Note: df102 0.320802 0.13496  
  C++ Note: df103 -9.12088 -6.18217  
  C++ Note: df104 0.617144 0.398893  
  C++ Note: df105 -0.0351723 -0.0218306  
  C++ Note: df106 -364.756 -867.031  
  C++ Note: riskr checked 13683.9  
  C++ Note: risk1r checked 38812.2 8366.11  
  C++ Note: risk2r checked 134810 8366.11  
  C++ Note: riskl checked 180.348  
  C++ Note: risk1l checked 561.69 120.669  
  C++ Note: risk2l checked 1971.73 120.669  
  C++ Note: df101 -117.015 -117.015  
  C++ Note: df102 0.320802 0.13496  
  C++ Note: df103 -9.12088 -6.18217  
  C++ Note: df104 0.617144 0.398893  
  C++ Note: df105 -0.0351723 -0.0218306  
  C++ Note: df106 -364.756 -867.031  
  C++ Note: df501 -117.0147
  C++ Note: df504 0.6171437 0.3988932  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,88,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 434 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 851.028 949.469  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: risk1r checked 3418.73 1095.31  
  C++ Note: risk2r checked 8667.81 1095.31  
  C++ Note: riskl checked 19.6098  
  C++ Note: risk1l checked 42.0717 11.5472  
  C++ Note: risk2l checked 118.124 11.5472  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df102 6.06579 2.41134  
  C++ Note: df103 -8.60689 -6.47374  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -0.70476 -0.37248  
  C++ Note: df106 -19.78 -49.7572  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.42857 0.17936  
  C++ Note: sums checked 2537.47 1104.32  
  C++ Note: risk checked 2796.31  
  C++ Note: risk1 checked 7446.21 1576.41  
  C++ Note: risk2 checked 26529.4 1576.41  
  C++ Note: riskr checked 7268.45  
  C++ Note: risk1r checked 18181.7 4116.59  
  C++ Note: risk2r checked 58803.1 4116.59  
  C++ Note: riskl checked 88.5975  
  C++ Note: risk1l checked 256.339 56.699  
  C++ Note: risk2l checked 862.409 56.699  
  C++ Note: df101 -117.373 -117.373  
  C++ Note: df102 1.78502 1.30975  
  C++ Note: df103 -8.96103 -6.38772  
  C++ Note: df104 0.42857 0.17936  
  C++ Note: df105 -0.199199 -0.205041  
  C++ Note: df106 -65.7541 -89.6148  
  C++ Note: df100 3507 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 7268.45  
  C++ Note: risk1r checked 18181.7 4116.59  
  C++ Note: risk2r checked 58803.1 4116.59  
  C++ Note: riskl checked 88.5975  
  C++ Note: risk1l checked 256.339 56.699  
  C++ Note: risk2l checked 862.409 56.699  
  C++ Note: df101 -117.373 -117.373  
  C++ Note: df102 1.78502 1.30975  
  C++ Note: df103 -8.96103 -6.38772  
  C++ Note: df104 0.42857 0.17936  
  C++ Note: df105 -0.199199 -0.205041  
  C++ Note: df106 -65.7541 -89.6148  
  C++ Note: ending guess 0
  C++ Note: df501 -117.3726
  C++ Note: df504 0.4285697 0.17936  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.4285697 0.17936, -117.3726<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.42857 0.17936  
  C++ Note: sums checked 2537.47 1104.32  
  C++ Note: risk checked 2796.31  
  C++ Note: risk1 checked 7446.21 1576.41  
  C++ Note: risk2 checked 26529.4 1576.41  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 7268.45  
  C++ Note: risk1r checked 18181.7 4116.59  
  C++ Note: risk2r checked 58803.1 4116.59  
  C++ Note: riskl checked 88.5975  
  C++ Note: risk1l checked 256.339 56.699  
  C++ Note: risk2l checked 862.409 56.699  
  C++ Note: df101 -117.373 -117.373  
  C++ Note: df102 1.78502 1.30975  
  C++ Note: df103 -8.96103 -6.38772  
  C++ Note: df104 0.42857 0.17936  
  C++ Note: df105 -0.199199 -0.205041  
  C++ Note: df106 -65.7541 -89.6148  
  C++ Note: Starting Halves
  C++ Note: df501 -117.3726
  C++ Note: df504 0.4285697 0.17936  
  C++ Note: values checked 0.577969 0.333141  
  C++ Note: sums checked 3883.17 1209.93  
  C++ Note: risk checked 4672.1  
  C++ Note: risk1 checked 14081.1 2784.48  
  C++ Note: risk2 checked 53455.8 2784.48  
  C++ Note: riskr checked 11783.5  
  C++ Note: risk1r checked 32618.6 7038.87  
  C++ Note: risk2r checked 111717 7038.87  
  C++ Note: riskl checked 152.934  
  C++ Note: risk1l checked 470.041 100.807  
  C++ Note: risk2l checked 1638.11 100.807  
  C++ Note: df101 -117.054 -117.054  
  C++ Note: df102 0.609162 0.503449  
  C++ Note: df103 -9.07577 -6.25818  
  C++ Note: df104 0.577969 0.333141  
  C++ Note: df105 -0.0671196 -0.0804466  
  C++ Note: df106 -192.156 -232.504  
  C++ Note: df100 7749 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 11783.5  
  C++ Note: risk1r checked 32618.6 7038.87  
  C++ Note: risk2r checked 111717 7038.87  
  C++ Note: riskl checked 152.934  
  C++ Note: risk1l checked 470.041 100.807  
  C++ Note: risk2l checked 1638.11 100.807  
  C++ Note: df101 -117.054 -117.054  
  C++ Note: df102 0.609162 0.503449  
  C++ Note: df103 -9.07577 -6.25818  
  C++ Note: df104 0.577969 0.333141  
  C++ Note: df105 -0.0671196 -0.0804466  
  C++ Note: df106 -192.156 -232.504  
  C++ Note: riskr checked 11783.5  
  C++ Note: risk1r checked 32618.6 7038.87  
  C++ Note: risk2r checked 111717 7038.87  
  C++ Note: riskl checked 152.934  
  C++ Note: risk1l checked 470.041 100.807  
  C++ Note: risk2l checked 1638.11 100.807  
  C++ Note: df101 -117.054 -117.054  
  C++ Note: df102 0.609162 0.503449  
  C++ Note: df103 -9.07577 -6.25818  
  C++ Note: df104 0.577969 0.333141  
  C++ Note: df105 -0.0671196 -0.0804466  
  C++ Note: df106 -192.156 -232.504  
  C++ Note: df501 -117.0539
  C++ Note: df504 0.5779686 0.3331409  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,72,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 484 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 2348 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 3202 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -122.8909<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 5569 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 6435 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,78,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 493 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 2392 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 3246 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -122.8909<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 5603 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 6498 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 2197.44  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -122.891 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,69,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 15624 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 17029 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 17601 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -119.9814<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 19188 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -239.963 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 31853 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,74,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 405 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 1917 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 10436 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: ending guess 0
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1 -0.1, -119.9814<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 24332 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df100 25039 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: riskr checked 2125.36  
  C++ Note: riskl checked 19.6098  
  C++ Note: df101 -119.981 0  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,74,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 517 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: derivs checked 1229.85 410.233  
  C++ Note: second derivs checked 3319.14 410.233  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: risk1r checked 3174.27 1089.12  
  C++ Note: risk2r checked 7204.63 1089.12  
  C++ Note: riskl checked 19.6098  
  C++ Note: risk1l checked 42.0717 11.5472  
  C++ Note: risk2l checked 118.124 11.5472  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df102 21.2331 3.11507  
  C++ Note: df103 -19.7104 -6.49727  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -1.07726 -0.479443  
  C++ Note: df106 -5.78769 -39.4505  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.732916 0.388699  
  C++ Note: sums checked 7921.99 7921.99  
  C++ Note: derivs checked 26681.9 4784.79  
  C++ Note: second derivs checked 107491 4784.79  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 7921.99  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 7921.99  
  C++ Note: risk checked 7921.99  
  C++ Note: risk1 checked 26681.9 4784.79  
  C++ Note: risk2 checked 107491 4784.79  
  C++ Note: riskr checked 15672.9  
  C++ Note: risk1r checked 42701.5 9198.27  
  C++ Note: risk2r checked 144140 9198.27  
  C++ Note: riskl checked 259.026  
  C++ Note: risk1l checked 843.134 168.735  
  C++ Note: risk2l checked 3047.41 168.735  
  C++ Note: df101 -110.801 -110.801  
  C++ Note: df102 6.10212 0.649377  
  C++ Note: df103 -15.9738 -6.28124  
  C++ Note: df104 0.732916 0.388699  
  C++ Note: df105 -0.382009 -0.103384  
  C++ Note: df106 -18.1578 -170.627  
  C++ Note: df100 35433 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: riskr checked 15672.9  
  C++ Note: risk1r checked 42701.5 9198.27  
  C++ Note: risk2r checked 144140 9198.27  
  C++ Note: riskl checked 259.026  
  C++ Note: risk1l checked 843.134 168.735  
  C++ Note: risk2l checked 3047.41 168.735  
  C++ Note: df101 -110.801 -110.801  
  C++ Note: df102 6.10212 0.649377  
  C++ Note: df103 -15.9738 -6.28124  
  C++ Note: df104 0.732916 0.388699  
  C++ Note: df105 -0.382009 -0.103384  
  C++ Note: df106 -18.1578 -170.627  
  C++ Note: ending guess 0
  C++ Note: df501 -110.8014
  C++ Note: df504 0.732916 0.3886995  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.732916 0.3886995, -110.8014<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.732916 0.388699  
  C++ Note: sums checked 7921.99 7921.99  
  C++ Note: derivs checked 26681.9 4784.79  
  C++ Note: second derivs checked 107491 4784.79  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 7921.99  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 7921.99  
  C++ Note: risk checked 7921.99  
  C++ Note: risk1 checked 26681.9 4784.79  
  C++ Note: risk2 checked 107491 4784.79  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 15672.9  
  C++ Note: risk1r checked 42701.5 9198.27  
  C++ Note: risk2r checked 144140 9198.27  
  C++ Note: riskl checked 259.026  
  C++ Note: risk1l checked 843.134 168.735  
  C++ Note: risk2l checked 3047.41 168.735  
  C++ Note: df101 -110.801 -110.801  
  C++ Note: df102 6.10212 0.649377  
  C++ Note: df103 -15.9738 -6.28124  
  C++ Note: df104 0.732916 0.388699  
  C++ Note: df105 -0.382009 -0.103384  
  C++ Note: df106 -18.1578 -170.627  
  C++ Note: Starting Halves
  C++ Note: df501 -110.8014
  C++ Note: df504 0.732916 0.3886995  
  C++ Note: values checked 1.02333 0.493704  
  C++ Note: sums checked 24538.9 24538.9  
  C++ Note: derivs checked 97084.4 15240.1  
  C++ Note: second derivs checked 428953 15240.1  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 24538.9  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 24538.9  
  C++ Note: risk checked 24538.9  
  C++ Note: risk1 checked 97084.4 15240.1  
  C++ Note: risk2 checked 428953 15240.1  
  C++ Note: riskr checked 39636.5  
  C++ Note: risk1r checked 128036 24066.7  
  C++ Note: risk2r checked 480878 24066.7  
  C++ Note: riskl checked 745.302  
  C++ Note: risk1l checked 2645.43 469.387  
  C++ Note: risk2l checked 10112.8 469.387  
  C++ Note: df101 -219.242 -219.242  
  C++ Note: df102 3.67875 0.282739  
  C++ Note: df103 -27.6208 -12.3546  
  C++ Note: df104 1.02333 0.493704  
  C++ Note: df105 -0.133188 -0.0228854  
  C++ Note: df106 -59.5969 -775.422  
  C++ Note: df100 95087 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: values checked 0.878122 0.441202  
  C++ Note: sums checked 13644.7 13644.7  
  C++ Note: derivs checked 50166.2 8351.52  
  C++ Note: second derivs checked 212275 8351.52  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 13644.7  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 13644.7  
  C++ Note: risk checked 13644.7  
  C++ Note: risk1 checked 50166.2 8351.52  
  C++ Note: risk2 checked 212275 8351.52  
  C++ Note: riskr checked 24463.6  
  C++ Note: risk1r checked 72901 14591.7  
  C++ Note: risk2r checked 260138 14591.7  
  C++ Note: riskl checked 434.83  
  C++ Note: risk1l checked 1482.72 278.946  
  C++ Note: risk2l checked 5521.8 278.946  
  C++ Note: df101 -220.1 -220.1  
  C++ Note: df102 7.78892 0.801531  
  C++ Note: df103 -29.6888 -12.4655  
  C++ Note: df104 0.878122 0.441202  
  C++ Note: df105 -0.262352 -0.0643001  
  C++ Note: df106 -28.2581 -274.599  
  C++ Note: df100 143102 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:31 2023
  
  C++ Note: Changing back to best
  C++ Note: values checked 0.732916 0.388699  
  C++ Note: sums checked 7921.99 7921.99  
  C++ Note: derivs checked 26681.9 4784.79  
  C++ Note: second derivs checked 107491 4784.79  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 7921.99  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 7921.99  
  C++ Note: risk checked 7921.99  
  C++ Note: risk1 checked 26681.9 4784.79  
  C++ Note: risk2 checked 107491 4784.79  
  C++ Note: riskr checked 15672.9  
  C++ Note: risk1r checked 42701.5 9198.27  
  C++ Note: risk2r checked 144140 9198.27  
  C++ Note: riskl checked 259.026  
  C++ Note: risk1l checked 843.134 168.735  
  C++ Note: risk2l checked 3047.41 168.735  
  C++ Note: df101 -110.801 -110.801  
  C++ Note: df102 6.10212 0.649377  
  C++ Note: df103 -15.9738 -6.28124  
  C++ Note: df104 0.732916 0.388699  
  C++ Note: df105 -0.382009 -0.103384  
  C++ Note: df106 -18.1578 -170.627  
  C++ Note: riskr checked 15672.9  
  C++ Note: risk1r checked 42701.5 9198.27  
  C++ Note: risk2r checked 144140 9198.27  
  C++ Note: riskl checked 259.026  
  C++ Note: risk1l checked 843.134 168.735  
  C++ Note: risk2l checked 3047.41 168.735  
  C++ Note: df101 -110.801 -110.801  
  C++ Note: df102 6.10212 0.649377  
  C++ Note: df103 -15.9738 -6.28124  
  C++ Note: df104 0.732916 0.388699  
  C++ Note: df105 -0.382009 -0.103384  
  C++ Note: df106 -18.1578 -170.627  
  C++ Note: df501 -110.8014
  C++ Note: df504 0.732916 0.3886995  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,71,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 528 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: derivs checked 1229.85 410.233  
  C++ Note: second derivs checked 3319.14 410.233  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2197.44  
  C++ Note: risk1r checked 3174.27 1089.12  
  C++ Note: risk2r checked 7204.63 1089.12  
  C++ Note: riskl checked 19.6098  
  C++ Note: risk1l checked 42.0717 11.5472  
  C++ Note: risk2l checked 118.124 11.5472  
  C++ Note: df101 -122.891 -122.891  
  C++ Note: df102 21.2331 3.11507  
  C++ Note: df103 -19.7104 -6.49727  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -1.07726 -0.479443  
  C++ Note: df106 -5.78769 -39.4505  
  C++ Note: Starting Halves
  C++ Note: df501 -122.8909
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.707943 0.259582  
  C++ Note: sums checked 6754.07 6754.07  
  C++ Note: derivs checked 22400.3 3873.99  
  C++ Note: second derivs checked 89482.9 3873.99  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 6754.07  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 6754.07  
  C++ Note: risk checked 6754.07  
  C++ Note: risk1 checked 22400.3 3873.99  
  C++ Note: risk2 checked 89482.9 3873.99  
  C++ Note: riskr checked 13607.5  
  C++ Note: risk1r checked 36518.1 7564.8  
  C++ Note: risk2r checked 122057 7564.8  
  C++ Note: riskl checked 219.94  
  C++ Note: risk1l checked 713.45 137.505  
  C++ Note: risk2l checked 2579.26 137.505  
  C++ Note: df101 -111.093 -111.093  
  C++ Note: df102 6.4244 1.45354  
  C++ Note: df103 -16.1091 -6.40177  
  C++ Note: df104 0.707943 0.259582  
  C++ Note: df105 -0.398805 -0.227053  
  C++ Note: df106 -17.2924 -76.4296  
  C++ Note: df100 6203 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: riskr checked 13607.5  
  C++ Note: risk1r checked 36518.1 7564.8  
  C++ Note: risk2r checked 122057 7564.8  
  C++ Note: riskl checked 219.94  
  C++ Note: risk1l checked 713.45 137.505  
  C++ Note: risk2l checked 2579.26 137.505  
  C++ Note: df101 -111.093 -111.093  
  C++ Note: df102 6.4244 1.45354  
  C++ Note: df103 -16.1091 -6.40177  
  C++ Note: df104 0.707943 0.259582  
  C++ Note: df105 -0.398805 -0.227053  
  C++ Note: df106 -17.2924 -76.4296  
  C++ Note: ending guess 0
  C++ Note: df501 -111.0934
  C++ Note: df504 0.7079435 0.259582  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.7079435 0.259582, -111.0934<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.707943 0.259582  
  C++ Note: sums checked 6754.07 6754.07  
  C++ Note: derivs checked 22400.3 3873.99  
  C++ Note: second derivs checked 89482.9 3873.99  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 6754.07  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 6754.07  
  C++ Note: risk checked 6754.07  
  C++ Note: risk1 checked 22400.3 3873.99  
  C++ Note: risk2 checked 89482.9 3873.99  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 13607.5  
  C++ Note: risk1r checked 36518.1 7564.8  
  C++ Note: risk2r checked 122057 7564.8  
  C++ Note: riskl checked 219.94  
  C++ Note: risk1l checked 713.45 137.505  
  C++ Note: risk2l checked 2579.26 137.505  
  C++ Note: df101 -111.093 -111.093  
  C++ Note: df102 6.4244 1.45354  
  C++ Note: df103 -16.1091 -6.40177  
  C++ Note: df104 0.707943 0.259582  
  C++ Note: df105 -0.398805 -0.227053  
  C++ Note: df106 -17.2924 -76.4296  
  C++ Note: Starting Halves
  C++ Note: df501 -111.0934
  C++ Note: df504 0.7079435 0.259582  
  C++ Note: values checked 1.00705 0.429872  
  C++ Note: sums checked 22129.4 22129.4  
  C++ Note: derivs checked 86917.6 13416  
  C++ Note: second derivs checked 382294 13416  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 22129.4  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 22129.4  
  C++ Note: risk checked 22129.4  
  C++ Note: risk1 checked 86917.6 13416  
  C++ Note: risk2 checked 382294 13416  
  C++ Note: riskr checked 36201.7  
  C++ Note: risk1r checked 115958 21431.5  
  C++ Note: risk2r checked 433026 21431.5  
  C++ Note: riskl checked 676.025  
  C++ Note: risk1l checked 2396.11 417.501  
  C++ Note: risk2l checked 9159.18 417.501  
  C++ Note: df101 -109.674 -109.674  
  C++ Note: df102 2.03825 0.531514  
  C++ Note: df103 -13.8822 -6.25712  
  C++ Note: df104 1.00705 0.429872  
  C++ Note: df105 -0.146825 -0.0849455  
  C++ Note: df106 -53.8081 -206.343  
  C++ Note: df100 26014 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: riskr checked 36201.7  
  C++ Note: risk1r checked 115958 21431.5  
  C++ Note: risk2r checked 433026 21431.5  
  C++ Note: riskl checked 676.025  
  C++ Note: risk1l checked 2396.11 417.501  
  C++ Note: risk2l checked 9159.18 417.501  
  C++ Note: df101 -109.674 -109.674  
  C++ Note: df102 2.03825 0.531514  
  C++ Note: df103 -13.8822 -6.25712  
  C++ Note: df104 1.00705 0.429872  
  C++ Note: df105 -0.146825 -0.0849455  
  C++ Note: df106 -53.8081 -206.343  
  C++ Note: riskr checked 36201.7  
  C++ Note: risk1r checked 115958 21431.5  
  C++ Note: risk2r checked 433026 21431.5  
  C++ Note: riskl checked 676.025  
  C++ Note: risk1l checked 2396.11 417.501  
  C++ Note: risk2l checked 9159.18 417.501  
  C++ Note: df101 -109.674 -109.674  
  C++ Note: df102 2.03825 0.531514  
  C++ Note: df103 -13.8822 -6.25712  
  C++ Note: df104 1.00705 0.429872  
  C++ Note: df105 -0.146825 -0.0849455  
  C++ Note: df106 -53.8081 -206.343  
  C++ Note: df501 -109.6742
  C++ Note: df504 1.007047 0.4298716  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,73,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 418 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: derivs checked 1229.85 410.233  
  C++ Note: second derivs checked 3319.14 410.233  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: risk1r checked 3418.73 1095.31  
  C++ Note: risk2r checked 8667.81 1095.31  
  C++ Note: riskl checked 19.6098  
  C++ Note: risk1l checked 42.0717 11.5472  
  C++ Note: risk2l checked 118.124 11.5472  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df102 6.06579 2.41134  
  C++ Note: df103 -8.60689 -6.47374  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -0.70476 -0.37248  
  C++ Note: df106 -19.78 -49.7572  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.497478 0.312164  
  C++ Note: sums checked 3648.05 3648.05  
  C++ Note: derivs checked 10299.6 2165.99  
  C++ Note: second derivs checked 37798.4 2165.99  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 3648.05  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 3648.05  
  C++ Note: risk checked 3648.05  
  C++ Note: risk1 checked 10299.6 2165.99  
  C++ Note: risk2 checked 37798.4 2165.99  
  C++ Note: riskr checked 9367.5  
  C++ Note: risk1r checked 24562.6 5580.77  
  C++ Note: risk2r checked 81557.6 5580.77  
  C++ Note: riskl checked 118.249  
  C++ Note: risk1l checked 351.472 78.443  
  C++ Note: risk2l checked 1199.14 78.443  
  C++ Note: df101 -117.142 -117.142  
  C++ Note: df102 1.31609 0.547704  
  C++ Note: df103 -9.05233 -6.2666  
  C++ Note: df104 0.497478 0.312164  
  C++ Note: df105 -0.145387 -0.0874005  
  C++ Note: df106 -89.0079 -213.879  
  C++ Note: df100 4077 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: riskr checked 9367.5  
  C++ Note: risk1r checked 24562.6 5580.77  
  C++ Note: risk2r checked 81557.6 5580.77  
  C++ Note: riskl checked 118.249  
  C++ Note: risk1l checked 351.472 78.443  
  C++ Note: risk2l checked 1199.14 78.443  
  C++ Note: df101 -117.142 -117.142  
  C++ Note: df102 1.31609 0.547704  
  C++ Note: df103 -9.05233 -6.2666  
  C++ Note: df104 0.497478 0.312164  
  C++ Note: df105 -0.145387 -0.0874005  
  C++ Note: df106 -89.0079 -213.879  
  C++ Note: ending guess 0
  C++ Note: df501 -117.1424
  C++ Note: df504 0.4974778 0.3121644  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.4974778 0.3121644, -117.1424<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.497478 0.312164  
  C++ Note: sums checked 3648.05 3648.05  
  C++ Note: derivs checked 10299.6 2165.99  
  C++ Note: second derivs checked 37798.4 2165.99  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 3648.05  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 3648.05  
  C++ Note: risk checked 3648.05  
  C++ Note: risk1 checked 10299.6 2165.99  
  C++ Note: risk2 checked 37798.4 2165.99  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 9367.5  
  C++ Note: risk1r checked 24562.6 5580.77  
  C++ Note: risk2r checked 81557.6 5580.77  
  C++ Note: riskl checked 118.249  
  C++ Note: risk1l checked 351.472 78.443  
  C++ Note: risk2l checked 1199.14 78.443  
  C++ Note: df101 -234.285 -234.285  
  C++ Note: df102 2.63218 1.09541  
  C++ Note: df103 -18.1047 -12.5332  
  C++ Note: df104 0.497478 0.312164  
  C++ Note: df105 -0.145387 -0.0874005  
  C++ Note: df106 -89.0079 -213.879  
  C++ Note: Starting Halves
  C++ Note: df501 -117.1424
  C++ Note: df504 0.4974778 0.3121644  
  C++ Note: values checked 0.617144 0.398893  
  C++ Note: sums checked 5479.95 5479.95  
  C++ Note: derivs checked 17006.9 3344.7  
  C++ Note: second derivs checked 65563.9 3344.7  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 5479.95  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 5479.95  
  C++ Note: risk checked 5479.95  
  C++ Note: risk1 checked 17006.9 3344.7  
  C++ Note: risk2 checked 65563.9 3344.7  
  C++ Note: riskr checked 13683.9  
  C++ Note: risk1r checked 38812.2 8366.11  
  C++ Note: risk2r checked 134810 8366.11  
  C++ Note: riskl checked 180.348  
  C++ Note: risk1l checked 561.69 120.669  
  C++ Note: risk2l checked 1971.73 120.669  
  C++ Note: df101 -117.015 -117.015  
  C++ Note: df102 0.320802 0.13496  
  C++ Note: df103 -9.12088 -6.18217  
  C++ Note: df104 0.617144 0.398893  
  C++ Note: df105 -0.0351723 -0.0218306  
  C++ Note: df106 -364.756 -867.031  
  C++ Note: df100 24627 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: riskr checked 13683.9  
  C++ Note: risk1r checked 38812.2 8366.11  
  C++ Note: risk2r checked 134810 8366.11  
  C++ Note: riskl checked 180.348  
  C++ Note: risk1l checked 561.69 120.669  
  C++ Note: risk2l checked 1971.73 120.669  
  C++ Note: df101 -117.015 -117.015  
  C++ Note: df102 0.320802 0.13496  
  C++ Note: df103 -9.12088 -6.18217  
  C++ Note: df104 0.617144 0.398893  
  C++ Note: df105 -0.0351723 -0.0218306  
  C++ Note: df106 -364.756 -867.031  
  C++ Note: riskr checked 13683.9  
  C++ Note: risk1r checked 38812.2 8366.11  
  C++ Note: risk2r checked 134810 8366.11  
  C++ Note: riskl checked 180.348  
  C++ Note: risk1l checked 561.69 120.669  
  C++ Note: risk2l checked 1971.73 120.669  
  C++ Note: df101 -117.015 -117.015  
  C++ Note: df102 0.320802 0.13496  
  C++ Note: df103 -9.12088 -6.18217  
  C++ Note: df104 0.617144 0.398893  
  C++ Note: df105 -0.0351723 -0.0218306  
  C++ Note: df106 -364.756 -867.031  
  C++ Note: df501 -117.0147
  C++ Note: df504 0.6171437 0.3988932  
  Note: 26 risk groups
  C++ Note: START_COX_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Term checked 0 0  
  C++ Note: df99,79,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Grouping Start
  C++ Note: df100 420 0 0 -1,Prep_List
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: starting subterms 1 in guess 0
  C++ Note: values checked -0.1 -0.1  
  C++ Note: sums checked 807.883 807.883  
  C++ Note: derivs checked 1229.85 410.233  
  C++ Note: second derivs checked 3319.14 410.233  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 807.883  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 807.883  
  C++ Note: risk checked 807.883  
  C++ Note: risk1 checked 1229.85 410.233  
  C++ Note: risk2 checked 3319.14 410.233  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 2125.36  
  C++ Note: risk1r checked 3418.73 1095.31  
  C++ Note: risk2r checked 8667.81 1095.31  
  C++ Note: riskl checked 19.6098  
  C++ Note: risk1l checked 42.0717 11.5472  
  C++ Note: risk2l checked 118.124 11.5472  
  C++ Note: df101 -119.981 -119.981  
  C++ Note: df102 6.06579 2.41134  
  C++ Note: df103 -8.60689 -6.47374  
  C++ Note: df104 -0.1 -0.1  
  C++ Note: df105 -0.70476 -0.37248  
  C++ Note: df106 -19.78 -49.7572  
  C++ Note: Starting Halves
  C++ Note: df501 -119.9814
  C++ Note: df504 -0.1 -0.1  
  C++ Note: values checked 0.42857 0.17936  
  C++ Note: sums checked 2796.31 2796.31  
  C++ Note: derivs checked 7446.21 1576.41  
  C++ Note: second derivs checked 26529.4 1576.41  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 2796.31  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 2796.31  
  C++ Note: risk checked 2796.31  
  C++ Note: risk1 checked 7446.21 1576.41  
  C++ Note: risk2 checked 26529.4 1576.41  
  C++ Note: riskr checked 7268.45  
  C++ Note: risk1r checked 18181.7 4116.59  
  C++ Note: risk2r checked 58803.1 4116.59  
  C++ Note: riskl checked 88.5975  
  C++ Note: risk1l checked 256.339 56.699  
  C++ Note: risk2l checked 862.409 56.699  
  C++ Note: df101 -117.373 -117.373  
  C++ Note: df102 1.78502 1.30975  
  C++ Note: df103 -8.96103 -6.38772  
  C++ Note: df104 0.42857 0.17936  
  C++ Note: df105 -0.199199 -0.205041  
  C++ Note: df106 -65.7541 -89.6148  
  C++ Note: df100 4003 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: riskr checked 7268.45  
  C++ Note: risk1r checked 18181.7 4116.59  
  C++ Note: risk2r checked 58803.1 4116.59  
  C++ Note: riskl checked 88.5975  
  C++ Note: risk1l checked 256.339 56.699  
  C++ Note: risk2l checked 862.409 56.699  
  C++ Note: df101 -117.373 -117.373  
  C++ Note: df102 1.78502 1.30975  
  C++ Note: df103 -8.96103 -6.38772  
  C++ Note: df104 0.42857 0.17936  
  C++ Note: df105 -0.199199 -0.205041  
  C++ Note: df106 -65.7541 -89.6148  
  C++ Note: ending guess 0
  C++ Note: df501 -117.3726
  C++ Note: df504 0.4285697 0.17936  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.4285697 0.17936, -117.3726<-- Best Guess
  C++ Note: starting subterms 1 in best guess 0
  C++ Note: values checked 0.42857 0.17936  
  C++ Note: sums checked 2796.31 2796.31  
  C++ Note: derivs checked 7446.21 1576.41  
  C++ Note: second derivs checked 26529.4 1576.41  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 2796.31  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 2796.31  
  C++ Note: risk checked 2796.31  
  C++ Note: risk1 checked 7446.21 1576.41  
  C++ Note: risk2 checked 26529.4 1576.41  
  C++ Note: Made Risk Side Lists
  C++ Note: riskr checked 7268.45  
  C++ Note: risk1r checked 18181.7 4116.59  
  C++ Note: risk2r checked 58803.1 4116.59  
  C++ Note: riskl checked 88.5975  
  C++ Note: risk1l checked 256.339 56.699  
  C++ Note: risk2l checked 862.409 56.699  
  C++ Note: df101 -117.373 -117.373  
  C++ Note: df102 1.78502 1.30975  
  C++ Note: df103 -8.96103 -6.38772  
  C++ Note: df104 0.42857 0.17936  
  C++ Note: df105 -0.199199 -0.205041  
  C++ Note: df106 -65.7541 -89.6148  
  C++ Note: Starting Halves
  C++ Note: df501 -117.3726
  C++ Note: df504 0.4285697 0.17936  
  C++ Note: values checked 0.577969 0.333141  
  C++ Note: sums checked 4672.1 4672.1  
  C++ Note: derivs checked 14081.1 2784.48  
  C++ Note: second derivs checked 53455.8 2784.48  
  C++ Note: dose checked 1000  
  C++ Note: non-dose checked 4672.1  
  C++ Note: LIN_non-dose checked 1000  
  C++ Note: PLIN_non-dose checked 1000  
  C++ Note: LOGLIN_non-dose checked 4672.1  
  C++ Note: risk checked 4672.1  
  C++ Note: risk1 checked 14081.1 2784.48  
  C++ Note: risk2 checked 53455.8 2784.48  
  C++ Note: riskr checked 11783.5  
  C++ Note: risk1r checked 32618.6 7038.87  
  C++ Note: risk2r checked 111717 7038.87  
  C++ Note: riskl checked 152.934  
  C++ Note: risk1l checked 470.041 100.807  
  C++ Note: risk2l checked 1638.11 100.807  
  C++ Note: df101 -117.054 -117.054  
  C++ Note: df102 0.609162 0.503449  
  C++ Note: df103 -9.07577 -6.25818  
  C++ Note: df104 0.577969 0.333141  
  C++ Note: df105 -0.0671196 -0.0804466  
  C++ Note: df106 -192.156 -232.504  
  C++ Note: df100 8737 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: riskr checked 11783.5  
  C++ Note: risk1r checked 32618.6 7038.87  
  C++ Note: risk2r checked 111717 7038.87  
  C++ Note: riskl checked 152.934  
  C++ Note: risk1l checked 470.041 100.807  
  C++ Note: risk2l checked 1638.11 100.807  
  C++ Note: df101 -117.054 -117.054  
  C++ Note: df102 0.609162 0.503449  
  C++ Note: df103 -9.07577 -6.25818  
  C++ Note: df104 0.577969 0.333141  
  C++ Note: df105 -0.0671196 -0.0804466  
  C++ Note: df106 -192.156 -232.504  
  C++ Note: riskr checked 11783.5  
  C++ Note: risk1r checked 32618.6 7038.87  
  C++ Note: risk2r checked 111717 7038.87  
  C++ Note: riskl checked 152.934  
  C++ Note: risk1l checked 470.041 100.807  
  C++ Note: risk2l checked 1638.11 100.807  
  C++ Note: df101 -117.054 -117.054  
  C++ Note: df102 0.609162 0.503449  
  C++ Note: df103 -9.07577 -6.25818  
  C++ Note: df104 0.577969 0.333141  
  C++ Note: df105 -0.0671196 -0.0804466  
  C++ Note: df106 -192.156 -232.504  
  C++ Note: df501 -117.0539
  C++ Note: df504 0.5779686 0.3331409  
  Warning: model covariate order changed
  C++ Note: START_POIS_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Term checked 0 1 2  
  C++ Note: df99,82,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  0.09838881917
  C++ Note: starting subterms 3 in guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: Starting Halves
  C++ Note: df501 -471.3444
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df100 17480 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df100 18255 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df100 19016 3 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df100 19784 4 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df100 20558 5 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 20642 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -471.3444 -471.3444 -471.3444  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: ending guess 0
  C++ Note: df501 -471.3444
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.1 0.1 0.01, -471.3444<-- Best Guess
  C++ Note: starting subterms 3 in best guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: Made Risk Side Lists
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: Starting Halves
  C++ Note: df501 -471.3444
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df100 22625 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df100 23374 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df100 36770 3 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df100 37606 4 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df100 38355 5 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 38437 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -471.3444 -471.3444 -471.3444  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df501 -471.3444
  C++ Note: df504 0.1 0.1 0.01  
  Warning: model covariate order changed
  C++ Note: START_POIS_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Term checked 0 1 2  
  C++ Note: df99,86,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  0.09838881917
  C++ Note: starting subterms 3 in guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: Starting Halves
  C++ Note: df501 -465.2924
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df100 4091 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df100 4866 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df100 5609 3 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df100 6387 4 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df100 7172 5 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 7252 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -465.2924 -465.2924 -465.2924  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: ending guess 0
  C++ Note: df501 -465.2924
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.1 0.1 0.01, -465.2924<-- Best Guess
  C++ Note: starting subterms 3 in best guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: Made Risk Side Lists
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: Starting Halves
  C++ Note: df501 -465.2924
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df100 19104 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df100 19899 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df100 20662 3 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df100 21431 4 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df100 22187 5 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 22270 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -465.2924 -465.2924 -465.2924  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df501 -465.2924
  C++ Note: df504 0.1 0.1 0.01  
  Warning: model covariate order changed
  C++ Note: START_POIS_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Term checked 0 1 2  
  C++ Note: df99,81,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  0.09838881917
  C++ Note: starting subterms 3 in guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: derivs checked 2718.62 2718.62 1673.67  
  C++ Note: second derivs checked 8364.23 8364.23 4753.83  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 135.897  
  C++ Note: risk1 checked 309.348 124.933 69.7559  
  C++ Note: risk2 checked 962.927 395.451 198.322  
  C++ Note: df101 -471.344 -471.344 -471.344  
  C++ Note: df102 -124.247 -51.5548 -11.1906  
  C++ Note: df103 -1092.3 -291.907 -98.4449  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 714.689
  C++ Note: df105 0.113748 0.176614 0.113673  
  C++ Note: df106 3.79361 9.14258 42.1198  
  C++ Note: Starting Halves
  C++ Note: df501 -471.3444
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked 0.0146893 -0.0324605 -0.0752551  
  C++ Note: sums checked 1030.15 937.864 889.534  
  C++ Note: derivs checked 2098.13 1823.68 1321.7  
  C++ Note: second derivs checked 6286.73 5380.03 3566.98  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1030.15 937.864 889.534  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1030.15 937.864 889.534  
  C++ Note: risk checked 97.8746  
  C++ Note: risk1 checked 197.186 64.0534 45.77  
  C++ Note: risk2 checked 588.838 189.93 123.527  
  C++ Note: df101 -464.056 -464.056 -464.056  
  C++ Note: df102 2.82658 1.74045 11.9442  
  C++ Note: df103 -667.565 -72.021 -20.8439  
  C++ Note: df104 0.0146893 -0.0324605 -0.0752551  
  C++ Note: Checking Deviance 700.111
  C++ Note: df105 -0.00423416 -0.0241659 -0.573033  
  C++ Note: df106 -164.176 -266.629 -38.8519  
  C++ Note: df100 19218 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 19317 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -464.0556 -464.0556 -464.0556  
  C++ Note: df102 2.826577 1.740452 11.94423  
  C++ Note: df103 -667.5653 -72.02104 -20.84386  
  C++ Note: df104 0.01468927 -0.03246053 -0.07525507  
  C++ Note: Checking Deviance 700.1112
  C++ Note: df105 -0.004234158 -0.02416588 -0.5730334  
  C++ Note: df106 -164.1758 -266.6294 -38.85188  
  C++ Note: df101 -464.056 -464.056 -464.056  
  C++ Note: df102 2.82658 1.74045 11.9442  
  C++ Note: df103 -667.565 -72.021 -20.8439  
  C++ Note: df104 0.0146893 -0.0324605 -0.0752551  
  C++ Note: Checking Deviance 700.111
  C++ Note: df105 -0.00423416 -0.0241659 -0.573033  
  C++ Note: df106 -164.176 -266.629 -38.8519  
  C++ Note: ending guess 0
  C++ Note: df501 -464.0556
  C++ Note: df504 0.01468927 -0.03246053 -0.07525507  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.01468927 -0.03246053 -0.07525507, -464.0556<-- Best Guess
  C++ Note: starting subterms 3 in best guess 0
  C++ Note: values checked 0.0146893 -0.0324605 -0.0752551  
  C++ Note: sums checked 1030.15 937.864 889.534  
  C++ Note: derivs checked 2098.13 1823.68 1321.7  
  C++ Note: second derivs checked 6286.73 5380.03 3566.98  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1030.15 937.864 889.534  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1030.15 937.864 889.534  
  C++ Note: risk checked 97.8746  
  C++ Note: risk1 checked 197.186 64.0534 45.77  
  C++ Note: risk2 checked 588.838 189.93 123.527  
  C++ Note: Made Risk Side Lists
  C++ Note: df101 -464.056 -464.056 -464.056  
  C++ Note: df102 2.82658 1.74045 11.9442  
  C++ Note: df103 -667.565 -72.021 -20.8439  
  C++ Note: df104 0.0146893 -0.0324605 -0.0752551  
  C++ Note: Checking Deviance 700.111
  C++ Note: df105 -0.00423416 -0.0241659 -0.573033  
  C++ Note: df106 -164.176 -266.629 -38.8519  
  C++ Note: Starting Halves
  C++ Note: df501 -464.0556
  C++ Note: df504 0.01468927 -0.03246053 -0.07525507  
  C++ Note: values checked 0.0178649 -0.0143361 0.35452  
  C++ Note: sums checked 1036.85 971.819 2037.08  
  C++ Note: derivs checked 2118.2 1924.16 4920.93  
  C++ Note: second derivs checked 6353.36 5710.95 16822.7  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1036.85 971.819 2037.08  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1036.85 971.819 2037.08  
  C++ Note: risk checked 139.714  
  C++ Note: risk1 checked 286.721 68.2446 171.558  
  C++ Note: risk2 checked 859.265 203.782 586.483  
  C++ Note: df101 -469.82 -469.82 -469.82  
  C++ Note: df102 -97.6226 -22.5078 -71.9184  
  C++ Note: df103 -971.996 -113.175 -527.063  
  C++ Note: df104 0.0178649 -0.0143361 0.35452  
  C++ Note: Checking Deviance 711.641
  C++ Note: df105 0.100435 0.198875 0.136451  
  C++ Note: df106 4.81262 20.8737 6.53269  
  C++ Note: df100 23229 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.0162771 -0.0233983 0.139632  
  C++ Note: sums checked 1033.49 954.614 1280.15  
  C++ Note: derivs checked 2108.14 1873.17 2453.11  
  C++ Note: second derivs checked 6319.95 5542.86 7503.6  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1033.49 954.614 1280.15  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1033.49 954.614 1280.15  
  C++ Note: risk checked 112.352  
  C++ Note: risk1 checked 228.309 66.1122 85.2358  
  C++ Note: risk2 checked 683.175 196.727 260.734  
  C++ Note: df101 -462.807 -462.807 -462.807  
  C++ Note: df102 -32.1129 -9.92162 -4.425  
  C++ Note: df103 -773.813 -90.1054 -151.179  
  C++ Note: df104 0.0162771 -0.0233983 0.139632  
  C++ Note: Checking Deviance 697.615
  C++ Note: df105 0.0414996 0.110111 0.0292699  
  C++ Note: df106 14.4119 46.6464 104.589  
  C++ Note: df100 24659 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 24744 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -462.8075 -462.8075 -462.8075  
  C++ Note: df102 -32.11293 -9.92162 -4.425  
  C++ Note: df103 -773.8133 -90.10538 -151.179  
  C++ Note: df104 0.01627708 -0.02339832 0.1396325  
  C++ Note: Checking Deviance 697.615
  C++ Note: df105 0.04149958 0.1101113 0.02926994  
  C++ Note: df106 14.41188 46.64636 104.5893  
  C++ Note: df101 -462.807 -462.807 -462.807  
  C++ Note: df102 -32.1129 -9.92162 -4.425  
  C++ Note: df103 -773.813 -90.1054 -151.179  
  C++ Note: df104 0.0162771 -0.0233983 0.139632  
  C++ Note: Checking Deviance 697.615
  C++ Note: df105 0.0414996 0.110111 0.0292699  
  C++ Note: df106 14.4119 46.6464 104.589  
  C++ Note: df501 -462.8075
  C++ Note: df504 0.01627708 -0.02339832 0.1396325  
  Warning: model covariate order changed
  C++ Note: START_POIS_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Term checked 0 1 2  
  C++ Note: df99,82,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  0.09838881917
  C++ Note: starting subterms 3 in guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: derivs checked 2718.62 2718.62 1673.67  
  C++ Note: second derivs checked 8364.23 8364.23 4753.83  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 117.158  
  C++ Note: risk1 checked 91.4329 91.4329 56.218  
  C++ Note: risk2 checked 281.351 281.351 159.656  
  C++ Note: df101 -465.292 -465.292 -465.292  
  C++ Note: df102 -21.7888 -21.7888 -0.293182  
  C++ Note: df103 -168.093 -168.093 -60.0059  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 702.585
  C++ Note: df105 0.129623 0.129623 0.00488589  
  C++ Note: df106 21.3547 21.3547 1587.04  
  C++ Note: Starting Halves
  C++ Note: df501 -465.2924
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked 0.00278264 0.00278264 0.00633558  
  C++ Note: sums checked 1005.61 1005.61 1010.4  
  C++ Note: derivs checked 2024.74 2024.74 1656.36  
  C++ Note: second derivs checked 6043.41 6043.41 4694.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1005.61 1005.61 1010.4  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1005.61 1005.61 1010.4  
  C++ Note: risk checked 101.568  
  C++ Note: risk1 checked 68.0928 68.0928 55.6366  
  C++ Note: risk2 checked 203.279 203.279 157.663  
  C++ Note: df101 -463.165 -463.165 -463.165  
  C++ Note: df102 -1.81947 -1.81947 9.13177  
  C++ Note: df103 -85.586 -85.586 -48.4168  
  C++ Note: df104 0.00278264 0.00278264 0.00633558  
  C++ Note: Checking Deviance 698.331
  C++ Note: df105 0.0212589 0.0212589 -0.188608  
  C++ Note: df106 254.561 254.561 -50.7202  
  C++ Note: df100 19131 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 19225 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -463.1653 -463.1653 -463.1653  
  C++ Note: df102 -1.819466 -1.819466 9.131773  
  C++ Note: df103 -85.58597 -85.58597 -48.41679  
  C++ Note: df104 0.002782639 0.002782639 0.006335584  
  C++ Note: Checking Deviance 698.3306
  C++ Note: df105 0.02125892 0.02125892 -0.1886076  
  C++ Note: df106 254.5612 254.5612 -50.72019  
  C++ Note: df101 -463.165 -463.165 -463.165  
  C++ Note: df102 -1.81947 -1.81947 9.13177  
  C++ Note: df103 -85.586 -85.586 -48.4168  
  C++ Note: df104 0.00278264 0.00278264 0.00633558  
  C++ Note: Checking Deviance 698.331
  C++ Note: df105 0.0212589 0.0212589 -0.188608  
  C++ Note: df106 254.561 254.561 -50.7202  
  C++ Note: ending guess 0
  C++ Note: df501 -463.1653
  C++ Note: df504 0.002782639 0.002782639 0.006335584  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.002782639 0.002782639 0.006335584, -463.1653<-- Best Guess
  C++ Note: starting subterms 3 in best guess 0
  C++ Note: values checked 0.00278264 0.00278264 0.00633558  
  C++ Note: sums checked 1005.61 1005.61 1010.4  
  C++ Note: derivs checked 2024.74 2024.74 1656.36  
  C++ Note: second derivs checked 6043.41 6043.41 4694.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1005.61 1005.61 1010.4  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1005.61 1005.61 1010.4  
  C++ Note: risk checked 101.568  
  C++ Note: risk1 checked 68.0928 68.0928 55.6366  
  C++ Note: risk2 checked 203.279 203.279 157.663  
  C++ Note: Made Risk Side Lists
  C++ Note: df101 -463.165 -463.165 -463.165  
  C++ Note: df102 -1.81947 -1.81947 9.13177  
  C++ Note: df103 -85.586 -85.586 -48.4168  
  C++ Note: df104 0.00278264 0.00278264 0.00633558  
  C++ Note: Checking Deviance 698.331
  C++ Note: df105 0.0212589 0.0212589 -0.188608  
  C++ Note: df106 254.561 254.561 -50.7202  
  C++ Note: Starting Halves
  C++ Note: df501 -463.1653
  C++ Note: df504 0.002782639 0.002782639 0.006335584  
  C++ Note: values checked -0.0131616 -0.0131616 0.147791  
  C++ Note: sums checked 974.083 974.083 1300.42  
  C++ Note: derivs checked 1930.88 1930.88 2515.25  
  C++ Note: second derivs checked 5733.12 5733.12 7728.35  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 974.083 974.083 1300.42  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 974.083 974.083 1300.42  
  C++ Note: risk checked 109.188  
  C++ Note: risk1 checked 64.9356 64.9356 84.482  
  C++ Note: risk2 checked 192.841 192.841 259.554  
  C++ Note: df101 -462.376 -462.376 -462.376  
  C++ Note: df102 -6.9006 -6.9006 -2.24561  
  C++ Note: df103 -83.4455 -83.4455 -149.584  
  C++ Note: df104 -0.0131616 -0.0131616 0.147791  
  C++ Note: Checking Deviance 696.752
  C++ Note: df105 0.0826959 0.0826959 0.0150124  
  C++ Note: df106 67.0052 67.0052 205.902  
  C++ Note: df100 22955 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 23050 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -462.3761 -462.3761 -462.3761  
  C++ Note: df102 -6.900601 -6.900601 -2.245612  
  C++ Note: df103 -83.44551 -83.44551 -149.5839  
  C++ Note: df104 -0.01316155 -0.01316155 0.1477913  
  C++ Note: Checking Deviance 696.7523
  C++ Note: df105 0.0826959 0.0826959 0.01501239  
  C++ Note: df106 67.0052 67.0052 205.9021  
  C++ Note: df101 -462.376 -462.376 -462.376  
  C++ Note: df102 -6.9006 -6.9006 -2.24561  
  C++ Note: df103 -83.4455 -83.4455 -149.584  
  C++ Note: df104 -0.0131616 -0.0131616 0.147791  
  C++ Note: Checking Deviance 696.752
  C++ Note: df105 0.0826959 0.0826959 0.0150124  
  C++ Note: df106 67.0052 67.0052 205.902  
  C++ Note: df501 -462.3761
  C++ Note: df504 -0.01316155 -0.01316155 0.1477913  
  Warning: model covariate order changed
  C++ Note: START_POIS_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Term checked 0 1 2  
  C++ Note: df99,71,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: starting subterms 3 in guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: Starting Halves
  C++ Note: df501 -4502.842
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df100 20934 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df100 21738 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df100 43346 3 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df100 49250 4 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df100 49945 5 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 50019 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -4502.842 -4502.842 -4502.842  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: ending guess 0
  C++ Note: df501 -4502.842
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.1 0.1 0.01, -4502.842<-- Best Guess
  C++ Note: starting subterms 3 in best guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: Made Risk Side Lists
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: Starting Halves
  C++ Note: df501 -4502.842
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df100 51874 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df100 52585 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df100 53323 3 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df100 54036 4 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df100 54744 5 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 54818 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -4502.842 -4502.842 -4502.842  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df501 -4502.842
  C++ Note: df504 0.1 0.1 0.01  
  Warning: model covariate order changed
  C++ Note: START_POIS_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Term checked 0 1 2  
  C++ Note: df99,102,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: starting subterms 3 in guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: Starting Halves
  C++ Note: df501 -3887.159
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df100 1796 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df100 2485 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df100 3162 3 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df100 3836 4 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df100 4535 5 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 4606 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -3887.159 -3887.159 -3887.159  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: ending guess 0
  C++ Note: df501 -3887.159
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, 0.1 0.1 0.01, -3887.159<-- Best Guess
  C++ Note: starting subterms 3 in best guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: Made Risk Side Lists
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: Starting Halves
  C++ Note: df501 -3887.159
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df100 6410 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df100 7080 2 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df100 7767 3 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df100 11285 4 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df100 12072 5 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 12155 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -3887.159 -3887.159 -3887.159  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df501 -3887.159
  C++ Note: df504 0.1 0.1 0.01  
  Warning: model covariate order changed
  C++ Note: START_POIS_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Term checked 0 1 2  
  C++ Note: df99,77,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: starting subterms 3 in guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: derivs checked 2718.62 2718.62 1673.67  
  C++ Note: second derivs checked 8364.23 8364.23 4753.83  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 4042.38  
  C++ Note: risk1 checked 9197.89 3714.54 2076.68  
  C++ Note: risk2 checked 28626.6 11756 5905.65  
  C++ Note: df101 -4502.84 -4502.84 -4502.84  
  C++ Note: df102 -10190.2 -4118.22 -2262.35  
  C++ Note: df103 -32478.6 -13186.7 -6507.03  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 8777.68
  C++ Note: df105 0.31375 0.3123 0.347677  
  C++ Note: df106 0.441881 1.09339 1.99034  
  C++ Note: Starting Halves
  C++ Note: df501 -4502.842
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked -0.135312 -0.134225 -0.250758  
  C++ Note: sums checked 775.813 777.287 703.399  
  C++ Note: derivs checked 1353.63 1357.82 843.789  
  C++ Note: second derivs checked 3851.14 3864.62 2040.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 775.813 777.287 703.399  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 775.813 777.287 703.399  
  C++ Note: risk checked 1947.44  
  C++ Note: risk1 checked 3229.56 932.875 650.753  
  C++ Note: risk2 checked 9047.51 2519.53 1569.29  
  C++ Note: df101 -2221.2 -2221.2 -2221.2  
  C++ Note: df102 -3430.31 -987.692 -680.114  
  C++ Note: df103 -10255.9 -2718.54 -1671  
  C++ Note: df104 -0.135312 -0.134225 -0.250758  
  C++ Note: Checking Deviance 4214.41
  C++ Note: df105 0.334472 0.363318 0.40701  
  C++ Note: df106 0.647523 2.24888 3.26593  
  C++ Note: df100 2991 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 3082 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -2221.204 -2221.204 -2221.204  
  C++ Note: df102 -3430.312 -987.6924 -680.1135  
  C++ Note: df103 -10255.91 -2718.536 -1670.998  
  C++ Note: df104 -0.1353123 -0.1342251 -0.250758  
  C++ Note: Checking Deviance 4214.409
  C++ Note: df105 0.3344717 0.3633177 0.4070103  
  C++ Note: df106 0.6475226 2.248883 3.265932  
  C++ Note: df101 -2221.2 -2221.2 -2221.2  
  C++ Note: df102 -3430.31 -987.692 -680.114  
  C++ Note: df103 -10255.9 -2718.54 -1671  
  C++ Note: df104 -0.135312 -0.134225 -0.250758  
  C++ Note: Checking Deviance 4214.41
  C++ Note: df105 0.334472 0.363318 0.40701  
  C++ Note: df106 0.647523 2.24888 3.26593  
  C++ Note: ending guess 0
  C++ Note: df501 -2221.204
  C++ Note: df504 -0.1353123 -0.1342251 -0.250758  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1353123 -0.1342251 -0.250758, -2221.204<-- Best Guess
  C++ Note: starting subterms 3 in best guess 0
  C++ Note: values checked -0.135312 -0.134225 -0.250758  
  C++ Note: sums checked 775.813 777.287 703.399  
  C++ Note: derivs checked 1353.63 1357.82 843.789  
  C++ Note: second derivs checked 3851.14 3864.62 2040.5  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 775.813 777.287 703.399  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 775.813 777.287 703.399  
  C++ Note: risk checked 1947.44  
  C++ Note: risk1 checked 3229.56 932.875 650.753  
  C++ Note: risk2 checked 9047.51 2519.53 1569.29  
  C++ Note: Made Risk Side Lists
  C++ Note: df101 -2221.2 -2221.2 -2221.2  
  C++ Note: df102 -3430.31 -987.692 -680.114  
  C++ Note: df103 -10255.9 -2718.54 -1671  
  C++ Note: df104 -0.135312 -0.134225 -0.250758  
  C++ Note: Checking Deviance 4214.41
  C++ Note: df105 0.334472 0.363318 0.40701  
  C++ Note: df106 0.647523 2.24888 3.26593  
  C++ Note: Starting Halves
  C++ Note: df501 -2221.204
  C++ Note: df504 -0.1353123 -0.1342251 -0.250758  
  C++ Note: values checked -0.386166 -0.406713 -0.556016  
  C++ Note: sums checked 530.805 517.075 517.73  
  C++ Note: derivs checked 685.958 650.815 431.761  
  C++ Note: second derivs checked 1763.64 1658.24 857.073  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 530.805 517.075 517.73  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 530.805 517.075 517.73  
  C++ Note: risk checked 1163.68  
  C++ Note: risk1 checked 1300.52 264.473 226.818  
  C++ Note: risk2 checked 3217.4 560.859 445.828  
  C++ Note: df101 -1419.31 -1419.31 -1419.31  
  C++ Note: df102 -1247.6 -255.914 -221.157  
  C++ Note: df103 -3647.6 -542.826 -444.472  
  C++ Note: df104 -0.386166 -0.406713 -0.556016  
  C++ Note: Checking Deviance 2610.62
  C++ Note: df105 0.342032 0.471448 0.497573  
  C++ Note: df106 1.13764 5.54603 6.41764  
  C++ Note: df100 6339 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 6414 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -1419.309 -1419.309 -1419.309  
  C++ Note: df102 -1247.596 -255.9143 -221.1574  
  C++ Note: df103 -3647.601 -542.8265 -444.4722  
  C++ Note: df104 -0.3861661 -0.4067135 -0.5560158  
  C++ Note: Checking Deviance 2610.618
  C++ Note: df105 0.342032 0.4714476 0.4975732  
  C++ Note: df106 1.137635 5.546034 6.417642  
  C++ Note: df101 -1419.31 -1419.31 -1419.31  
  C++ Note: df102 -1247.6 -255.914 -221.157  
  C++ Note: df103 -3647.6 -542.826 -444.472  
  C++ Note: df104 -0.386166 -0.406713 -0.556016  
  C++ Note: Checking Deviance 2610.62
  C++ Note: df105 0.342032 0.471448 0.497573  
  C++ Note: df106 1.13764 5.54603 6.41764  
  C++ Note: df501 -1419.309
  C++ Note: df504 -0.3861661 -0.4067135 -0.5560158  
  Warning: model covariate order changed
  C++ Note: START_POIS_GUESS
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: Term checked 0 1 2  
  C++ Note: df99,83,Starting
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: starting subterms 3 in guess 0
  C++ Note: values checked 0.1 0.1 0.01  
  C++ Note: sums checked 1234.36 1234.36 1016.5  
  C++ Note: derivs checked 2718.62 2718.62 1673.67  
  C++ Note: second derivs checked 8364.23 8364.23 4753.83  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 1234.36 1234.36 1016.5  
  C++ Note: risk checked 3485.21  
  C++ Note: risk1 checked 2718.62 2718.62 1673.67  
  C++ Note: risk2 checked 8364.23 8364.23 4753.83  
  C++ Note: df101 -3887.16 -3887.16 -3887.16  
  C++ Note: df102 -2996.4 -2996.4 -1814.45  
  C++ Note: df103 -9336.51 -9336.51 -5219.74  
  C++ Note: df104 0.1 0.1 0.01  
  C++ Note: Checking Deviance 7546.32
  C++ Note: df105 0.320934 0.320934 0.347613  
  C++ Note: df106 1.29727 1.29727 2.14234  
  C++ Note: Starting Halves
  C++ Note: df501 -3887.159
  C++ Note: df504 0.1 0.1 0.01  
  C++ Note: values checked -0.140701 -0.140701 -0.25071  
  C++ Note: sums checked 768.575 768.575 703.44  
  C++ Note: derivs checked 1333.06 1333.06 843.888  
  C++ Note: second derivs checked 3785.08 3785.08 2040.81  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 768.575 768.575 703.44  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 768.575 768.575 703.44  
  C++ Note: risk checked 2240.59  
  C++ Note: risk1 checked 1333.06 1333.06 843.888  
  C++ Note: risk2 checked 3785.08 3785.08 2040.81  
  C++ Note: df101 -2535.64 -2535.64 -2535.64  
  C++ Note: df102 -1430.54 -1430.54 -889.835  
  C++ Note: df103 -4142.14 -4142.14 -2191.1  
  C++ Note: df104 -0.140701 -0.140701 -0.25071  
  C++ Note: Checking Deviance 4843.27
  C++ Note: df105 0.345363 0.345363 0.406112  
  C++ Note: df106 1.7725 1.7725 2.84956  
  C++ Note: df100 2886 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 2976 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -2535.637 -2535.637 -2535.637  
  C++ Note: df102 -1430.54 -1430.54 -889.8347  
  C++ Note: df103 -4142.138 -4142.138 -2191.104  
  C++ Note: df104 -0.1407007 -0.1407007 -0.2507095  
  C++ Note: Checking Deviance 4843.274
  C++ Note: df105 0.3453627 0.3453627 0.4061125  
  C++ Note: df106 1.772503 1.772503 2.849559  
  C++ Note: df101 -2535.64 -2535.64 -2535.64  
  C++ Note: df102 -1430.54 -1430.54 -889.835  
  C++ Note: df103 -4142.14 -4142.14 -2191.1  
  C++ Note: df104 -0.140701 -0.140701 -0.25071  
  C++ Note: Checking Deviance 4843.27
  C++ Note: df105 0.345363 0.345363 0.406112  
  C++ Note: df106 1.7725 1.7725 2.84956  
  C++ Note: ending guess 0
  C++ Note: df501 -2535.637
  C++ Note: df504 -0.1407007 -0.1407007 -0.2507095  
  C++ Note: Refreshing matrices after all guesses
  C++ Note: Guess Results
  Guess number, parameter values, Log-Likelihood
  0, -0.1407007 -0.1407007 -0.2507095, -2535.637<-- Best Guess
  C++ Note: starting subterms 3 in best guess 0
  C++ Note: values checked -0.140701 -0.140701 -0.25071  
  C++ Note: sums checked 768.575 768.575 703.44  
  C++ Note: derivs checked 1333.06 1333.06 843.888  
  C++ Note: second derivs checked 3785.08 3785.08 2040.81  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 768.575 768.575 703.44  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 768.575 768.575 703.44  
  C++ Note: risk checked 2240.59  
  C++ Note: risk1 checked 1333.06 1333.06 843.888  
  C++ Note: risk2 checked 3785.08 3785.08 2040.81  
  C++ Note: Made Risk Side Lists
  C++ Note: df101 -2535.64 -2535.64 -2535.64  
  C++ Note: df102 -1430.54 -1430.54 -889.835  
  C++ Note: df103 -4142.14 -4142.14 -2191.1  
  C++ Note: df104 -0.140701 -0.140701 -0.25071  
  C++ Note: Checking Deviance 4843.27
  C++ Note: df105 0.345363 0.345363 0.406112  
  C++ Note: df106 1.7725 1.7725 2.84956  
  C++ Note: Starting Halves
  C++ Note: df501 -2535.637
  C++ Note: df504 -0.1407007 -0.1407007 -0.2507095  
  C++ Note: values checked -0.399723 -0.399723 -0.555294  
  C++ Note: sums checked 521.666 521.666 518.042  
  C++ Note: derivs checked 662.529 662.529 432.38  
  C++ Note: second derivs checked 1693.3 1693.3 858.703  
  C++ Note: dose checked 1000 1000 1000  
  C++ Note: non-dose checked 521.666 521.666 518.042  
  C++ Note: LIN_non-dose checked 1000 1000 1000  
  C++ Note: PLIN_non-dose checked 1000 1000 1000  
  C++ Note: LOGLIN_non-dose checked 521.666 521.666 518.042  
  C++ Note: risk checked 1561.37  
  C++ Note: risk1 checked 662.529 662.529 432.38  
  C++ Note: risk2 checked 1693.3 1693.3 858.703  
  C++ Note: df101 -1824.35 -1824.35 -1824.35  
  C++ Note: df102 -677.073 -677.073 -433.523  
  C++ Note: df103 -1781.54 -1781.54 -884.003  
  C++ Note: df104 -0.399723 -0.399723 -0.555294  
  C++ Note: Checking Deviance 3420.71
  C++ Note: df105 0.380049 0.380049 0.490409  
  C++ Note: df106 2.69447 2.69447 4.2082  
  C++ Note: df100 17010 1 1 0,Update_calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df100 17101 0 0 0,Update_Calc
  C++ Note: Current Time, Fri Sep 29 06:01:32 2023
  
  C++ Note: df101 -1824.353 -1824.353 -1824.353  
  C++ Note: df102 -677.0727 -677.0727 -433.5231  
  C++ Note: df103 -1781.539 -1781.539 -884.0028  
  C++ Note: df104 -0.3997228 -0.3997228 -0.5552939  
  C++ Note: Checking Deviance 3420.707
  C++ Note: df105 0.3800493 0.3800493 0.4904092  
  C++ Note: df106 2.694472 2.694472 4.208203  
  C++ Note: df101 -1824.35 -1824.35 -1824.35  
  C++ Note: df102 -677.073 -677.073 -433.523  
  C++ Note: df103 -1781.54 -1781.54 -884.003  
  C++ Note: df104 -0.399723 -0.399723 -0.555294  
  C++ Note: Checking Deviance 3420.71
  C++ Note: df105 0.380049 0.380049 0.490409  
  C++ Note: df106 2.69447 2.69447 4.2082  
  C++ Note: df501 -1824.353
  C++ Note: df504 -0.3997228 -0.3997228 -0.5552939  
  [ FAIL 1 | WARN 0 | SKIP 0 | PASS 945 ]
  
  ══ Failed tests ════════════════════════════════════════════════════════════════
  ── Failure ('test-omnibus.R:419:5'): check deviation calc ──────────────────────
  `devs` (`actual`) not equal to c(0.6091269, 0.5356671, 0.7385757, 0.9448081) (`expected`).
  
    `actual`: 0.4307 0.5357 0.7386 0.9448
  `expected`: 0.6091 0.5357 0.7386 0.9448
  
  [ FAIL 1 | WARN 0 | SKIP 0 | PASS 945 ]
  Error: Test failures
  Execution halted